SGD^TM is a scientific database of the molecular biology and genetics of the yeast Saccharomyces cerevisiae, which is commonly known as baker's or budding yeast.

SGD sends out its quarterly newsletter to colleagues designated as contacts in SGD. An HTML version of the newsletter is available. If you would like to receive this letter in the future please use the Colleague Submission/Update form to let us know.

• Genome Snapshot
• New papers added to SGD this week.
• View Genome-wide Analysis papers in SGD.
• Do a literature search.
• Table of Gene Summary Paragraphs (new ones highlighted yellow).

A large set of genetic interaction data from Costanzo et al., The Genetic Landscape of a Cell, Science 327: 425-431 (2010) is available for download from SGD's Download Data Files page and will be available via the web interface in the future. This study presents 74,984 genetic interactions, comprising a functional map of the cell. Thanks to the authors for providing their data to SGD.

SGD curators periodically update the systematic sequence and its annotation. Information regarding changes can be found via the Summary of Chromosome Sequence and Annotation Updates and in the "Locus History" pages of affected features. Files on the SGD FTP site are updated weekly.

Between 2010-01-04 and 2010-01-05, two new ncRNAs were annotated on Chromosome IX, the annotation of ORF DIA2/YOR080W was changed, and the sequence of Chromosome XIV was changed, affecting the annotation of ORF SAL1/YNL083W.

The following changes will be made to files available for download from SGD in February 2010:

• All files available in http://downloads.yeastgenome.org/gene_registry/ will be obsoleted. This means that they will no longer be available to download.

• The annotation_change.tab file will also be obsoleted. This means this file will no longer be available to download. For information regarding ORF qualifiers (Verified, Uncharacterized, Dubious), please use the already available SGD_features.tab file. Information regarding deleted or merged chromosomal features can be found in the new deleted_merged_features.tab file (described below).

• A new file called deleted_merged_features.tab will be available from http://downloads.yeastgenome.org/chromosomal_feature/. This file will list chromosomal features that have been deleted or merged. The format of the file is identical to the annotation_change.tab file.

The Saccharomyces Genome Database (SGD^TM) project is supported by a P41 grant, National Resources [HG001315], from the National Human Genome Research Institute at the US National Institutes of Health.   The SGD^TM project is located in the Department of Genetics at the School of Medicine, Stanford University. The trademark on SGD^TM is held by The Board of Trustees, Leland Stanford Junior University.

Database Copyright © 1997-2010 The Board of Trustees, Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. How to cite SGD.