Gene Ontology Help

SDS22-GLC7 phosphatase complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Protein phosphatase complex implicated in acting in opposition to the Chromosomal Passenger complex (CPX-1900) at the kinetochore. Glc7 dephosphorylation of kinetochore proteins promotes mitotic spindle attachment. The opposing Chromosomal Passenger complex and Glc7 activities ensure that chromosomes achieve a bipolar attachment to the spindle. SDS22 appears to both act as a targeting subunit for the enzyme and also to regulate phosphatase activity.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

hydrolase activity, phosphatase activity, chromosome organization, nucleus, organelle