About SGD

The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae along with search and analysis tools to explore these data, enabling the discovery of functional relationships between sequence and gene products in fungi and higher organisms.

Meetings

Fungal Pathogen Genomics
May 07 to May 12, 2023 -

Wellcome Genome Campus, Hinxton, Cambridge, UK

TAGC2024 The Allied Genetics Conference
March 05 to March 10, 2024 -

National Harbor | Washington DC Metro Area

New & Noteworthy

Regulation of yeast inducible promoters by SAGA and TFIID - November 15, 2022

Gene transcription — the elaborate process that our cells use to read genetic information stored in DNA – was long thought to be turned on only when certain regulatory factors traveled to specific DNA sequences. In a new study published in Genes & Development, Mittal et al., 2022, discovered that a subset of genes has their transcription […]

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2D RNA structures from RNAcentral - October 20, 2022

SGD has updated our RNA pages to add secondary structures provided by RNAcentral and generated by R2DT. Thumbnails and linkouts to RNAcentral via RNAcentral IDs are shown on the Summary and Sequence pages. Interactive secondary structure viewers are available on the Sequence pages. Take the pages for a spin! For more information about the structures, please see […]

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Role of Sumoylation in Regulating Replication - September 09, 2022

There are ~400 origins of replication in yeast, each of which can be “licensed” by the binding of the conserved origin recognition complex (ORC) and then the MCM replicative helicase complex, all of which happens in G1 phase. During the subsequent S phase, origins are then “activated” by binding of several other replication factors, leading […]

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Humanizing Glycolysis in Yeast - September 02, 2022

While glycolysis is highly conserved between unicellular yeast and multicellular humans, it appears that not only the glycolytic functions but also the secondary (aka “moonlighting”) functions of the relevant proteins remain largely consistent. This consistency presents unique opportunities for better understanding human glycolysis in muscle tissue and elsewhere. The technical challenges of studying glycolytic enzymes […]

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Link Between Aging and Iron - August 25, 2022

Perturbations in iron homeostasis affect aging, but how this happens has remained a bit of a black box. A new study by Patnaik et al. in Cell Reports illuminates this box by looking more closely at the transcription factors that are first to respond when iron becomes limiting. Key among these are Atf1p and Atf2p, […]

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