About SGD

The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae along with search and analysis tools to explore these data, enabling the discovery of functional relationships between sequence and gene products in fungi and higher organisms.

Meetings

36th International Specialised Symposium on Yeasts (ISSY36): Yeast in the Genomics Era
July 12 to July 15, 2022 -

University of British Columbia, Vancouver, BC

The Yeast Chromosome Biology and Cell Cycle Conference
July 17 to July 21, 2022 -

Southbridge, MA

CSHL Yeast Genetics & Genomics course
July 26 to August 15, 2022 -

Cold Spring Harbor Laboratory, New York

Yeast Genetics Meeting 2022
August 17 to August 21, 2022 -

University of California, Los Angeles

Fungal Pathogen Genomics
May 07 to May 12, 2023 -

Wellcome Genome Campus, Hinxton, Cambridge, UK

New & Noteworthy

The Remarkable Nuclear Pore Complex - June 24, 2022

The nuclear pore complex (NPC) is a complicated assembly embedded in the nuclear envelope that has the ability not only to assemble and disassemble quickly, but to adapt to changing needs for transport of macromolecules. The critical function of this elaborate complex has led researchers to invest intensive study, which has recently yielded remarkable new […]

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Mpe1p essential for mRNA processing - June 17, 2022

Messenger RNA (mRNA) 3′ end processing is an evolutionarily conserved and highly controlled process which requires several components from translation/transcription machinery. This processing involves monitoring nascent mRNAs for specific sequences, endonucleolytic cleavage, adding poly(A) tails, and triggering transcription termination. In budding yeast, the 3′ end processing machinery involves the cleavage and polyadenylation factor (CPF) complex […]

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Chromatin Modulators Act in Fungal Drug Resistance - June 10, 2022

Candida glabrata and Saccharomyces cerevisiae are closely related yeasts of which the former is pathogenic to mammals and the latter is used to make bread, wine, and beer. At present, the ~400,000 annual cases of life-threatening Candida infection are at risk of increase due to multidrug-resistant strains.  Fungal drug resistance relies on the fungal-specific pleiotropic […]

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New Twist on INO80 Chromatin Remodeling - June 03, 2022

The INO80 chromatin remodeling complex has long been the subject of intense study. Despite this, a recent report by Hsieh et al. in Molecular Cell reveals a new and unexpected biological activity: the INO80 complex (as compared to the other classes of chromatin remodelers) has a unique ability to act not only on nucleosomes but […]

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HIR Complex Influences Transcription Interference - May 27, 2022

Eukaryotic transcription is most often initiated by RNA polymerase II (RNAPII) and regulated by several factors, including epigenetic factors, histone modification, DNA methylation, and non-coding antisense transcripts. Non-coding antisense transcripts, produced from the strand opposite to the sense strand, use transcription interference (TI) to regulate gene expression. TI is a phenomenon where one transcription activity […]

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