Chemical: 2-oxoglutarate(2-)
- Chemical Name
- 2-oxoglutarate(2-)
- Chebi ID
- CHEBI:16810
- Definition
- An oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid.
- Structure
-
- Synonyms
- 2-ketoglutarate; 2-oxoglutarate; 2-oxopentanedioate; 2-oxopentanedioic acid, ion(2-); alpha-ketoglutarate
Phenotype Annotations
Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
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| Evidence ID | Analyze ID | Gene | Gene Systematic Name | Phenotype | Experiment Type | Experiment Type Category | Mutant Information | Strain Background | Chemical | Details | Reference |
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Pathways
- 2-oxoglutarate decarboxylation to succinyl-CoA
- 4-aminobutyrate degradation
- L-alanine biosynthesis II
- L-alanine degradation III
- L-arginine biosynthesis II (acetyl cycle)
- L-arginine degradation VI (arginase 2 pathway)
- L-asparagine biosynthesis I
- L-aspartate biosynthesis
- L-glutamate biosynthesis IV
- L-histidine biosynthesis
- L-isoleucine biosynthesis I (from threonine)
- L-leucine biosynthesis
- L-lysine biosynthesis IV
- L-lysine degradation III
- L-serine biosynthesis I
- L-tyrosine degradation III
- L-valine biosynthesis
- TCA cycle, aerobic respiration
- arginine degradation (aerobic)
- asparagine degradation
- aspartate biosynthesis
- glutamate biosynthesis from ammonia
- glutamate degradation I
- glutamate degradation IX
- isoleucine degradation
- leucine degradation
- phenylalanine biosynthesis
- phenylalanine degradation
- superpathway of L-threonine biosynthesis
- superpathway of TCA cycle and glyoxylate cycle
- superpathway of aromatic amino acid biosynthesis
- superpathway of branched chain amino acid biosynthesis
- superpathway of chorismate metabolism
- superpathway of glutamate biosynthesis
- superpathway of histidine, purine, and pyrimidine biosynthesis
- superpathway of serine and glycine biosynthesis
- superpathway of threonine and methionine biosynthesis
- superpathway of threonine biosynthesis
- tryptophan degradation
- tyrosine biosynthesis
- valine degradation
Shared Chemicals
This diagram displays Gene Ontology terms (green), phenotypes (blue), and macromolecular complexes (yellow) that are shared between the given chemical (black) and other chemicals (purple). The shared GO terms, phenotypes or complexes can be visualized separately using the radio button at the bottom of the graph.