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Dataset: Single cell functional genomics reveals the importance of mitochondria in cell-to-cell phenotypic variation

External ID
GSE104343
Reference
Dhar R, et al. (2019)
Channels
1
Conditions
4
Description
Yeast cells were stained with TMRE, which measures mitochondrial membrane potential, and were sorted onto four bins - HI,M1,M2 and LO, from TMRE vs cell-size plot. Total RNA was isolated from cells and RNA sequencing was done to compare transcriptome profile in sub-population of cells that differ in mitochondrial membrane potential. Cells with high potential showed repression of respiration genes, exhibited signs of DNA damage and iron deficiency.
Categories
organelles, biogenesis, structure, and function, transcriptome

Conditions

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Condition External ID