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Gene Ontology Term: negative cofactor 2 complex

GO ID
GO:0017054
Aspect
Cellular Component
Description
A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini.
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Annotations

Manually Curated 4 entries for 2 genes

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Gene/ComplexQualifierGene Ontology TermAnnotation ExtensionEvidenceSourceAssigned OnReference
NCB2part ofnegative cofactor 2 complexIDASGD2013-08-07Goppelt A and Meisterernst M (1996) PMID:8948634
NCB2part ofnegative cofactor 2 complexIPI with BUR6SGD2013-12-10Kim S, et al. (1997) PMID:9023340
BUR6part ofnegative cofactor 2 complexIPI with NCB2SGD2013-12-10Kim S, et al. (1997) PMID:9023340
BUR6part ofnegative cofactor 2 complexIDASGD2013-08-07Goppelt A and Meisterernst M (1996) PMID:8948634
Showing 1 to 4 of 4 entries

High-throughput 0 entries for 0 genes

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

Computational 5 entries for 2 genes

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference
cellular component (1386)