methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

Gene Ontology Term: methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

GO ID: GO:0019243
Aspect: Biological Process
Description: The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
Synonyms: D-lactate biosynthesis from methylglyoxal, D-lactate biosynthetic process from methylglyoxal, glyoxalase system, methylglyoxal breakdown to D-lactate, methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione, methylglyoxal degradation to D-lactate, methylglyoxal detoxification

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Annotations

Manually Curated 8 entries for 4 genes

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Gene/Complex	Qualifier	Gene Ontology Term	Evidence	Source	Assigned On	Reference
GLO2	involved in	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IMP	SGD	2014-02-04	Bito A, et al. (1997) PMID:9261170
GLO2	involved in	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IGI with GLO4	SGD	2014-02-04	Bito A, et al. (1997) PMID:9261170
GLO2	involved in	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IDA	SGD	2013-08-07	Bito A, et al. (1997) PMID:9261170
HSP31	involved in	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IDA	SGD	2013-12-16	Hasim S, et al. (2014) PMID:24302734
GLO1	involved in	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IDA	SGD	2013-08-07	Inoue Y and Kimura A (1996) PMID:8824231
GLO4	involved in	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IGI with GLO2	SGD	2014-02-04	Bito A, et al. (1997) PMID:9261170
GLO4	involved in	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IDA	SGD	2013-08-07	Bito A, et al. (1997) PMID:9261170
GLO4	involved in	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IMP	SGD	2014-02-04	Bito A, et al. (1997) PMID:9261170

Gene/Complex

Qualifier

Gene Ontology Term

Annotation Extension

Evidence

Source

Assigned On

Reference

GLO2

involved in

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

IMP