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Gene Ontology Term: nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay

GO ID
GO:0070478
Aspect
Biological Process
Description
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
Synonyms
3'-5' NMD, 3'-5' nonsense-mediated decay, 3'-5' nonsense-mediated mRNA decay, nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay
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Manually Curated 19 entries for 9 genes

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Gene/ComplexQualifierGene Ontology TermAnnotation ExtensionEvidenceSourceAssigned OnReference
Nonsense-mediated decay complexinvolved innuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decayBSRComplexPortal2018-03-27Leeds P, et al. (1992) PMID:1569946
SKI8involved innuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decayIGI with DCP1SGD2013-08-07Takahashi S, et al. (2003) PMID:12881429
SKI8involved innuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decayIMPSGD2013-08-07Takahashi S, et al. (2003) PMID:12881429
UPF3involved innuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decayIGI with XRN1SGD2013-08-07Takahashi S, et al. (2003) PMID:12881429
SKI6involved innuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decayIGI with DCP1SGD2013-08-07Takahashi S, et al. (2003) PMID:12881429
SKI6involved innuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decayIGI with DCP1SGD2013-08-07Mitchell P and Tollervey D (2003) PMID:12769863
SKI6involved innuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decayIMPSGD2013-08-07Takahashi S, et al. (2003) PMID:12881429
NMD2involved innuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decayIGI with XRN1SGD2013-08-07Takahashi S, et al. (2003) PMID:12881429
SKI2involved innuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decayIMPSGD2013-08-07Takahashi S, et al. (2003) PMID:12881429
SKI2involved innuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decayIGI with DCP1SGD2013-08-07Mitchell P and Tollervey D (2003) PMID:12769863
Showing 1 to 10 of 19 entries

High-throughput 0 entries for 0 genes

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

Computational 4 entries for 1 gene

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference
mRNA metabolic process (6)