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Gene Ontology Term: PAS complex

GO ID
GO:0070772
Aspect
Cellular Component
Description
A phosphatidylinositol kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKFYVE in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.
Synonyms
autophagy-specific phosphatidylinositol 3-kinase complex
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Annotations

Manually Curated 13 entries for 5 genes

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Gene/ComplexQualifierGene Ontology TermAnnotation ExtensionEvidenceSourceAssigned OnReference
FAB1part ofPAS complexIPI with VAC14SGD2013-08-07Jin N, et al. (2008) PMID:19037259
FAB1part ofPAS complexIDASGD2013-08-07Jin N, et al. (2008) PMID:19037259
ATG18part ofPAS complexIPI with VAC14SGD2013-08-07Jin N, et al. (2008) PMID:19037259
ATG18part ofPAS complexIDASGD2013-08-07Jin N, et al. (2008) PMID:19037259
VAC14part ofPAS complexIDASGD2013-08-07Jin N, et al. (2008) PMID:19037259
VAC14part ofPAS complexIPI with VAC7SGD2013-08-07Jin N, et al. (2008) PMID:19037259
VAC14part ofPAS complexIPI with FAB1SGD2013-08-07Jin N, et al. (2008) PMID:19037259
VAC14part ofPAS complexIPI with ATG18SGD2013-08-07Jin N, et al. (2008) PMID:19037259
VAC14part ofPAS complexIPI with FIG4SGD2013-08-07Jin N, et al. (2008) PMID:19037259
VAC7part ofPAS complexIPI with VAC14SGD2013-08-07Jin N, et al. (2008) PMID:19037259
Showing 1 to 10 of 13 entries

High-throughput 0 entries for 0 genes

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

Computational 5 entries for 2 genes

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference
catalytic complex (0)