negative regulation of protein import into nucleus during spindle assembly checkpoint

Gene Ontology Term: negative regulation of protein import into nucleus during spindle assembly checkpoint

GO ID: GO:1901925
Aspect: Biological Process
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p).
Synonyms: Kap121p transport inhibitory pathway, KTIP, negative regulation of protein import into nucleus during mitotic cell cycle spindle assembly checkpoint

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Annotations

Manually Curated 4 entries for 4 genes

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Gene/Complex	Qualifier	Gene Ontology Term	Annotation Extension	Evidence	Source	Assigned On	Reference
MAD1	involved in	negative regulation of protein import into nucleus during spindle assembly checkpoint		IMP	SGD	2013-08-07	Cairo LV, et al. (2013) PMID:23177738
MLP2	involved in	negative regulation of protein import into nucleus during spindle assembly checkpoint	has input PHO4	IGI with MLP1	SGD	2014-09-30	Cairo LV, et al. (2013) PMID:23177738
MLP1	involved in	negative regulation of protein import into nucleus during spindle assembly checkpoint	has input PHO4	IGI with MLP2	SGD	2014-09-30	Cairo LV, et al. (2013) PMID:23177738
IPL1	involved in	negative regulation of protein import into nucleus during spindle assembly checkpoint		IMP	SGD	2013-08-07	Cairo LV, et al. (2013) PMID:23177738

Gene/Complex

Qualifier

Gene Ontology Term

Annotation Extension

Evidence

Source

Assigned On

Reference

MAD1

involved in

negative regulation of protein import into nucleus during spindle assembly checkpoint

IMP