Click on a phenotype to go to its specific page within SGD; drag any of the phentoype objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram.
Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| ALK1 | cell cycle progression in anaphase: premature | classical genetics | null Allele: alk1-Δ | W303 | 100 µM latrunculin A | Treatment: alpha factor block release Details: reduced response to latrunculin A, with nuclear division in 42% of cells compared to 11% in wt, and spindle elongation with 29% anaphase spindles 4 hours after release from a G1 block | Galli M, et al. (2020) PMID:33585466 |
| BFR1 | cell cycle progression in anaphase: delayed | classical genetics | null Allele: bfr1-Δ | W303 | Details: subpopulation of large budded cells with a short spindle, inside the mother or bud neck | Xue Z, et al. (1996) PMID:8913743 | |
| BUB1 | cell cycle progression in anaphase: premature | classical genetics Anchor-away technique was used to prevent the protein from entering the nucleus | reduction of function | W303 | Cairo G, et al. (2020) PMID:32328625 | ||
| BUB3 | cell cycle progression in anaphase: premature | classical genetics Anchor-away technique was used to prevent the protein from entering the nucleus | reduction of function | W303 | Cairo G, et al. (2020) PMID:32328625 | ||
| CDC5 | cell cycle progression in anaphase: arrested | classical genetics | reduction of function Allele: cdc5-L158G cdc5-as1 (analog-sensitive) | W303 | Treatment: chloromethylketone (CMK) | Snead JL, et al. (2007) PMID:18022565 | |
| CIN8 | cell cycle progression in anaphase: delayed | classical genetics | null Allele: cin8-Δ | W303 | Straight AF, et al. (1998) PMID:9813090 | ||
| CLN3 | cell cycle progression in anaphase: decreased duration | classical genetics | overexpression | W303 | Treatment: alpha factor block release Details: decreased duration of anaphase in synchronized cells released from a G1 phase arrest where expression is induced after 15% of cells have undergone bud emergence | Brambila A, et al. (2024) PMID:38231863 | |
| KIP1 | cell cycle progression in anaphase: increased duration | classical genetics | null Allele: kip1-Δ | W303 | Details: determined by the average time between the separation of sister chromatids and the breakdown of the spindle | Straight AF, et al. (1998) PMID:9813090 | |
| KIP3 | cell cycle progression in anaphase: increased duration | classical genetics | null Allele: kip3-Δ | W303 | Details: determined by the average time between the separation of sister chromatids and the breakdown of the spindle | Straight AF, et al. (1998) PMID:9813090 | |
| NDC80 | cell cycle progression in anaphase: abnormal | classical genetics | conditional Allele: ndc80-1 Q2L, S73N, K122R, H313R, N321S, E389V, E429D, T473S, I490V, D556G, K613I, H648R, I658T; additional mutations modify C-terminal residues from IEELRNLEFETEHNVTN* to LKSYEIWSLKLNITLQMHKINDI* | Other | Temperature: elevated temperature, 36 °C Details: poles separate but somewhat dispersed DNA remains at one pole, resulting in the accumulation of large aploid buds containing SPBs but little DNA | Wigge PA, et al. (1998) PMID:9585415 |