Reference: Balasubramanian MK and Tao EY (2013) Timing it right: precise ON/OFF switches for Rho1 and Cdc42 GTPases in cytokinesis. J Cell Biol 202(2):187-9

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Abstract


In many eukaryotes, cytokinesis requires an actomyosin contractile ring that is crucial for cell constriction and new membrane organization. Two studies in this issue (Onishi et al. 2013. J. Cell Biol. http://dx.doi.org.10.1083/jcb.201302001 and Atkins et al. 2013. J. Cell Biol. http://dx.doi.org.10.1083/jcb.201301090) establish that precise activation and/or inactivation of Rho1 and Cdc42 GTPases is important for the correct order and successful completion of events downstream of actomyosin ring constriction in budding yeast.

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Comment | Journal Article | Research Support, Non-U.S. Gov't
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Balasubramanian MK, Tao EY
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