Chen L and Madura K (2014)

Abstract

The ubiquitin/proteasome system has been characterized extensively, although the site of nuclear substrate turnover has not been established definitively. We report here that two well-characterized nuclear proteins are stabilized in nuclear export mutants in Saccharomyces cerevisiae. The requirement for nuclear export defines a new regulatory step in intracellular proteolysis.

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Reference Type: Journal Article | Research Support, N.I.H., Extramural
Authors: Chen L, Madura K
Primary Lit For: STS1 | CRM1 | NUP116
Additional Lit For: RAD4 | RPN11 | PUP1 | POL1
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