Reference: Henry NL, et al. (1996) A yeast transcriptional stimulatory protein similar to human PC4. J Biol Chem 271(36):21842-7

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Abstract


A yeast protein has been identified that stimulates basal transcription by RNA polymerase II, binds both single- and double-stranded DNA, and interacts with both a general transcription factor and a transcriptional activator. Phosphorylation appears to regulate these interactions. The gene for the transcriptional stimulatory protein, termed TSP1, was cloned and found to be dispensable for yeast cell viability. The deduced amino acid sequence is similar to that of mammalian coactivator protein PC4.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.
Authors
Henry NL, Bushnell DA, Kornberg RD
Primary Lit For
SUB1 | DNA-directed RNA polymerase II complex

Interaction Annotations


Genetic Interactions

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Interactor Interactor Allele Assay Annotation Action Phenotype SGA score P-value Source Reference

Physical Interactions 1 entry for 2 genes

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InteractorInteractorAssayAnnotationActionModification
SUB1SUA7Reconstituted Complexmanually curatedHit-BaitNo Modification
Showing 1 to 1 of 1 entries