Xiao W, et al. (1994)

Abstract

The MAG1 gene encodes a 3-methyladenine DNA glycoslyase, which is involved in DNA alkylation repair in Saccharomyces cerevisiae. The mag1 mutant is deficient in 3-methyladenine DNA glycosylase activity and shows enhanced sensitivity to several monofunctional alkylating agents. MAG1 is allelic to MMS5. This gene has been previously located on chromosome V by chromosomal hybridization. We present physical and genetic mapping data here showing that the MAG1 gene is located on chromosome V-R, proximal to and about 10 kilobase pairs away from the SPT15 gene coding for the yeast TATA-binding protein TFIID.

PMID: 7941752
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Reference Type: Journal Article | Research Support, Non-U.S. Gov't
Authors: Xiao W, Penugonde V, Rank GH
Primary Lit For: MAG1 | General transcription factor complex TFIID
Additional Lit For: SPT15
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