AboutBlogDownloadExploreHelpGet Data

Reference: Njagi GD and Kilbey BJ (1982) cdc7-1 a temperature sensitive cell-cycle mutant which interferes with induced mutagenesis in Saccharomyces cerevisiae. Mol Gen Genet 186(4):478-81

Reference Help

Abstract

The mutant cdc7-1 is shown here to block UV induced reversion of six different auxotrophic mutations and forward mutations at several genes concerned with adenine biosynthesis in Saccharomyces cerevisiae. Chemical mutagenesis is also drastically reduced. In its effect on mutagenesis cdc7-1 resembles rad6-1. However, in contrast to rad6-1, cdc7-1 does not affect sporulation or mitotic recombination neither is it sensitive to the antifolate drug trimethoprim. It appears to fall in the same epistatic group as rad6-1. Possible explanations for its action are briefly considered.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't
Authors
Njagi GD, Kilbey BJ
Primary Lit For
Additional Lit For
Review For

Phenotype Annotations

Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

Gene Phenotype Experiment Type Mutant Information Strain Background Chemical Details Reference