The eight class I, set 1 super-suppressor genes, SUP2, SUP3, SUP4,\nSUP5, SUP6, SUP7, SUP8 and SUP11 are not closely linked and map at\ndistinct loci throughout the genome of yeast. Each of these\nsuppressors causes the production of 5 to 10% of the normal amount of\niso-1-cytochrome c when it is individually coupled to the ochre (UAA)\nmutant cy1-2. All eight iso-l-cytochromes c contain a residue of\ntyrosine at position 20 which corresponds to the site of the ochre\ncodon. Several of these super-suppressors also were shown to act on\ncy1-9, but at a much lower efficiency. It was shown that\niso-1-cytochrome c from one of the suppressed cyl-9 strains contains a\ntyrosine at position 2, which corresponds to the site of the ochre\noodon in this mutant. It is suggested that the gene product of the\neight super-suppressors is tyrosine transfer RNA.
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| Evidence ID | Analyze ID | Gene/Complex | Systematic Name/Complex Accession | Qualifier | Gene Ontology Term ID | Gene Ontology Term | Aspect | Annotation Extension | Evidence | Method | Source | Assigned On | Reference |
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| Evidence ID | Analyze ID | Gene | Gene Systematic Name | Phenotype | Experiment Type | Experiment Type Category | Mutant Information | Strain Background | Chemical | Details | Reference |
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| Evidence ID | Analyze ID | Gene | Gene Systematic Name | Disease Ontology Term | Disease Ontology Term ID | Qualifier | Evidence | Method | Source | Assigned On | Reference |
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| Evidence ID | Analyze ID | Regulator | Regulator Systematic Name | Target | Target Systematic Name | Direction | Regulation of | Happens During | Regulator Type | Direction | Regulation Of | Happens During | Method | Evidence | Strain Background | Reference |
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| Site | Modification | Modifier | Source | Reference |
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| Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Allele | Assay | Annotation | Action | Phenotype | SGA score | P-value | Source | Reference | Note |
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| Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Assay | Annotation | Action | Modification | Source | Reference | Note |
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| Complement ID | Locus ID | Gene | Species | Gene ID | Strain background | Direction | Details | Source | Reference |
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| Evidence ID | Analyze ID | Dataset | Description | Keywords | Number of Conditions | Reference |
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