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Reference: Hiraishi H, et al. (2006) Enhancement of stress tolerance in Saccharomyces cerevisiae by overexpression of ubiquitin ligase Rsp5 and ubiquitin-conjugating enzymes. Biosci Biotechnol Biochem 70(11):2762-5

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Abstract

Yeast Saccharomyces cerevisiae cells overexpressing essential ubiquitin ligase Rsp5 or ubiquitin-conjugating enzymes (Ubc1-Ubc13) showed tolerance to various stresses. Co-overexpression of Rsp5 and Ubc1, Ubc2, Ubc3, Ubc5, Ubc6, Ubc9, Ubc10, Ubc11, Ubc12, or Ubc13 further enhanced stress tolerance. These results suggest that overexpression of ubiquitin-related enzymes might be a useful method for breeding novel stress-resistant strains.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't
Authors
Hiraishi H, Mochizuki M, Takagi H
Primary Lit For
CDC34 | PEX4 | UBC5 | UBC6 | UBC13 | UBC1 | UBC9 | RAD6 | RSP5 | UBC12 | UBC11 ... Show all

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Gene Phenotype Experiment Type Mutant Information Strain Background Chemical Details Reference

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Interactor Interactor Assay Annotation Action Modification Source Reference