Reference: Pick E, et al. (2009) PCI complexes: Beyond the proteasome, CSN, and eIF3 Troika. Mol Cell 35(3):260-4

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Abstract


The bipartite PCI domain serves as the principal scaffold for proteasome lid, CSN, and eIF3, complexes that influence protein life span. PCI domains are also found in newly identified complexes directing nucleic acid regulation. The breadth of functions associated with the extended PCI family is a factor of shared subunits, among them a common factor Sem1/DSS1 that facilitates complex assembly.

Reference Type
Journal Article | Review
Authors
Pick E, Hofmann K, Glickman MH
Primary Lit For
Eukaryotic translation initiation factor 3 core complex
Review For
RPG1 | YJR084W | RPN9 | RPN6 | RPN12 | RPN3 | PCI8 | SAC3 | SEM1 | RPN11 | CSN9 | ... Show all