Reference: Sanudo M, et al. (2011) 1H, 13C, and 15N chemical shift assignments of ZCCHC9. Biomol NMR Assign 5(1):19-21

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Abstract


ZCCHC9 is a human nuclear protein with sequence homology to yeast Air1p/Air2p proteins which are RNA-binding subunits of the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex involved in nuclear RNA quality control and degradation in yeast. The ZCCHC9 protein contains four retroviral-type zinc knuckle motifs. Here, we report the NMR spectral assignment of the zinc knuckle region of ZCCHC9. These data will allow performing NMR structural and RNA-binding studies of ZCCHC9 with the aim to investigate its role in the RNA quality control in human.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't
Authors
Sanudo M, Jacko M, Rammelt C, Vanacova S, Stefl R
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