AboutBlogDownloadExploreHelpGet Data

Reference: Struhl K (2007) Transcriptional noise and the fidelity of initiation by RNA polymerase II. Nat Struct Mol Biol 14(2):103-5

Reference Help

Abstract

Eukaryotes transcribe much of their genomes, but little is known about the fidelity of transcriptional initiation by RNA polymerase II in vivo. I suggest that 90% of Pol II initiation events in yeast represent transcriptional noise, and that the specificity of initiation is comparable to that of DNA-binding proteins and other biological processes. This emphasizes the need to develop criteria that distinguish transcriptional noise from transcription with a biological function.

Reference Type
Journal Article
Authors
Struhl K
Primary Lit For
DNA-directed RNA polymerase II complex
Review For
RPB9 | RPB7 | RPB4 | RPC10 | RPB5 | RPO21 | RPB3 | RPO26 | RPB11 | RPB10 | RPB8 | ... Show all