Daily exposure to extremely low frequency magnetic fields (ELF MF) in the environment has raised public concerns on human health. Epidemiological studies suggest that exposure to ELF MF might associate with an elevated risk of cancer and other diseases in humans. To explain and/or support epidemiological observations, many laboratory studies have been conducted to elucidate the biological effects of ELF MF exposure and the underlying mechanisms of action. In order to reveal the global effects of ELF MF on protein expression, the proteomics approaches has been employed in this research field. In 2005, WHO organized a Workshop on Application of Proteomics and Transcriptomics in electromagnetic fields (EMF) Research in Helsinki, Finland to discuss the related problems and solutions. Later the journal Proteomics published a special issue devoted to the application of proteomics to EMF research. This chapter aims to summarize the current research progress and discuss the applicability of proteomics approaches in studying on ELF MF induced biological effects and the underlying mechanisms.
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Evidence ID | Analyze ID | Gene/Complex | Systematic Name/Complex Accession | Qualifier | Gene Ontology Term ID | Gene Ontology Term | Aspect | Annotation Extension | Evidence | Method | Source | Assigned On | Reference |
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Evidence ID | Analyze ID | Gene | Gene Systematic Name | Phenotype | Experiment Type | Experiment Type Category | Mutant Information | Strain Background | Chemical | Details | Reference |
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Evidence ID | Analyze ID | Gene | Gene Systematic Name | Disease Ontology Term | Disease Ontology Term ID | Qualifier | Evidence | Method | Source | Assigned On | Reference |
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Evidence ID | Analyze ID | Regulator | Regulator Systematic Name | Target | Target Systematic Name | Direction | Regulation of | Happens During | Regulator Type | Direction | Regulation Of | Happens During | Method | Evidence | Strain Background | Reference |
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Site | Modification | Modifier | Source | Reference |
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Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Allele | Assay | Annotation | Action | Phenotype | SGA score | P-value | Source | Reference | Note |
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Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Assay | Annotation | Action | Modification | Source | Reference | Note |
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Complement ID | Locus ID | Gene | Species | Gene ID | Strain background | Direction | Details | Source | Reference |
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Evidence ID | Analyze ID | Dataset | Description | Keywords | Number of Conditions | Reference |
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