This paper describes a new type of mitochondrial mutation. During germination of ascospores the mutants are blocked at the first budding stage and consequently die. However, vegetative growth on nonfermentable carbon sources and respiration are close to normal. The spores of the mutants which (like the wild type) contain very low amounts of mitochondrial cytochromes, do not synthesize cytochromes b and aa3 during germination.The mutants show a pleiotropic phenotype during the vegetative phase: they lack carbon catabolite repression of cytochromes on media containing 10% glucose. We discuss here the hypothesis that the mutation is located in a regulatory region on the mitochondrial genome which is needed for the reinitiation of mitochondrial genetic activity during germination of ascospores.
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Evidence ID | Analyze ID | Gene/Complex | Systematic Name/Complex Accession | Qualifier | Gene Ontology Term ID | Gene Ontology Term | Aspect | Annotation Extension | Evidence | Method | Source | Assigned On | Reference |
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Evidence ID | Analyze ID | Gene | Gene Systematic Name | Phenotype | Experiment Type | Experiment Type Category | Mutant Information | Strain Background | Chemical | Details | Reference |
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Evidence ID | Analyze ID | Gene | Gene Systematic Name | Disease Ontology Term | Disease Ontology Term ID | Qualifier | Evidence | Method | Source | Assigned On | Reference |
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Evidence ID | Analyze ID | Regulator | Regulator Systematic Name | Target | Target Systematic Name | Direction | Regulation of | Happens During | Regulator Type | Direction | Regulation Of | Happens During | Method | Evidence | Strain Background | Reference |
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Site | Modification | Modifier | Source | Reference |
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Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Allele | Assay | Annotation | Action | Phenotype | SGA score | P-value | Source | Reference | Note |
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Complement ID | Locus ID | Gene | Species | Gene ID | Strain background | Direction | Details | Source | Reference |
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Evidence ID | Analyze ID | Dataset | Description | Keywords | Number of Conditions | Reference |
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