In Nucleic Acids Res., we issued a correction for our article, Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics (Nucleic Acids Res. 31: 4119-4128, 2003). This paper reported eight new noncoding RNA genes in yeast, named RUF1 through RUF8, for "RNA of Unknown Function." We subsequently found that we cannot verify the transcription of three of the eight RUF loci (RUF4, RUF6, RUF7); the originally published results for these three RNAs appear to be experimental artifacts. Another locus, RUF8, is in fact a coding mRNA composed of three exons, and has recently been independently identified as SUS1, a protein component of the SAGA complex and the nuclear pore-associated mRNA export machinery (Rodriguez-Navarro et al., Cell 116: 75-86, 2004).

Reference Type

Personal Communication to SGD

Authors

McCutcheon JP, Eddy SR

Primary Lit For

SAGA complex

Additional Lit For

Review For