Reference: Lorch Y and Kornberg RD (2015) Chromatin-remodeling and the initiation of transcription. Q Rev Biophys 48(4):465-70

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Abstract


The nucleosome serves as a general gene repressor by the occlusion of regulatory and promoter DNA sequences. Repression is relieved by the SWI/SNF-RSC family of chromatin-remodeling complexes. Research reviewed here has revealed the essential features of the remodeling process.

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Journal Article | Research Support, N.I.H., Extramural | Review
Authors
Lorch Y, Kornberg RD
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