Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
14 entries for 9 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
---|---|---|---|---|---|---|---|
RPS13 | cell size: decreased | heterozygous diploid, systematic mutation set analysis of cell size for mutants in the systematic deletion collection | null Allele: rps13-Δ | S288C | Details: mutant is among the smallest 5% of heterozygous diploid deletion strains | Jorgensen P, et al. (2002) PMID:12089449 | |
RPS13 | competitive fitness: decreased | heterozygous diploid, competitive growth genome-wide fitness profiling | null Allele: rps13-Δ | S288C | Media: YPD Details: Relative fitness score: 0.893 | Deutschbauer AM, et al. (2005) PMID:15716499 | |
RPS13 | haploinsufficient | heterozygous diploid, competitive growth | null Allele: rps13-Δ | S288C | Deutschbauer AM, et al. (2005) PMID:15716499 | ||
RPS13 | haploinsufficient | heterozygous diploid, competitive growth genome-wide fitness profiling | null Allele: rps13-Δ | S288C | Media: turbidostat growth in FPM medium Details: Relative growth score: -0.0252 | Pir P, et al. (2012) PMID:22244311 | |
RPS13 | haploinsufficient | heterozygous diploid, systematic mutation set | null Allele: rps13-Δ | S288C | Ohnuki S and Ohya Y (2018) PMID:29768403 | ||
RPS13 | heat sensitivity: increased | heterozygous diploid, systematic mutation set pooled screening for fitness defects at 37 deg C relative to 30 deg C | null Allele: rps13-Δ | S288C | Temperature: elevated temperature, 37 °C | Sinha H, et al. (2008) PMID:18780730 | |
RPS13 | innate thermotolerance: increased | heterozygous diploid, systematic mutation set | null Allele: rps13-Δ | S288C | Phase: exponential phase Treatment: heat shock, 50 °C Details: resistance scale of 1 (least) to 4 (most) resistant: 1 | Jarolim S, et al. (2013) PMID:24142923 | |
RPS13 | inviable | systematic mutation set | null Allele: rps13-Δ | S288C | Giaever G, et al. (2002) PMID:12140549 | ||
RPS13 | inviable | classical genetics | null Allele: rps13-Δ | S288C | Steffen KK, et al. (2012) PMID:22377630 | ||
RPS13 | oxidative stress resistance: decreased | heterozygous diploid, systematic mutation set | null Allele: rps13-Δ | S288C | 3 mM hydrogen peroxide | Okada N, et al. (2014) PMID:24410772 |
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
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