Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
10 entries for 8 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
---|---|---|---|---|---|---|---|
SDH3 | chromosome/plasmid maintenance: decreased | heterozygous diploid, systematic mutation set | null Allele: sdh3-Δ | S288C | Assay: diploid bimater (BiM) assay Details: haploinsufficiency results in chromosome instability (CIN); scored >= 2 standard deviations above the mean | Choy JS, et al. (2013) PMID:23825022 | |
SDH3 | haploinsufficient | heterozygous diploid, competitive growth genome-wide fitness profiling | null Allele: sdh3-Δ | S288C | Media: turbidostat growth in FPM medium Details: Relative growth score: -0.0028 | Pir P, et al. (2012) PMID:22244311 | |
SDH3 | inviable | systematic mutation set | null Allele: sdh3-Δ | S288C | Giaever G, et al. (2002) PMID:12140549 | ||
SDH3 | petite-negative | classical genetics | null Allele: sdh3-Δ | Other | Gebert N, et al. (2011) PMID:22152483 | ||
SDH3 | resistance to chemicals: decreased | heterozygous diploid, systematic mutation set | null Allele: sdh3-Δ | S288C | 625 μg/mL sulfanilamide | Lum PY, et al. (2004) PMID:14718172 | |
SDH3 | resistance to chemicals: decreased | classical genetics | null Allele: sdh3-Δ | Other | 1.0 mM paraquat | Szeto SSW, et al. (2007) PMID:17636259 | |
SDH3 | respiratory growth: decreased rate | classical genetics | null Allele: sdh3-Δ | Other | Media: rich medium containing glycerol as sole carbon source | Kubo Y, et al. (2000) PMID:16232921 | |
SDH3 | vegetative growth: decreased | classical genetics | null Allele: sdh3-Δ | S288C | Details: poor growth when URA3 is deleted, but not when prototrophic for uracil | Sadhu MJ, et al. (2018) PMID:29632376 | |
SDH3 | vegetative growth: decreased | classical genetics | null Allele: sdh3-Δ | Other | Szeto SSW, et al. (2007) PMID:17636259 | ||
SDH3 | viable | classical genetics | null Allele: sdh3-Δ | S288C | Details: viable with poor growth when URA3 is deleted, but not when prototrophic for uracil | Sadhu MJ, et al. (2018) PMID:29632376 |
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
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