Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
10 entries for 10 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| YGL177W | competitive fitness: decreased | systematic mutation set | null Allele: ygl177w-Δ | S288C | Media: synthetic oak exudate medium, OAK | Qian W, et al. (2012) PMID:23103169 | |
| YGL177W | competitive fitness: increased | competitive growth fitness profiling using complete deletion alleles | null Allele: ygl177w-Δ | S288C | Media: minimal medium Details: Relative fitness score: 1.012 | Breslow DK, et al. (2008) PMID:18622397 | |
| YGL177W | filamentous growth: decreased | systematic mutation set | null Allele: ygl177w-Δ | Sigma1278b | Jin R, et al. (2008) PMID:17989363 | ||
| YGL177W | haploproficient | heterozygous diploid, competitive growth genome-wide fitness profiling | null Allele: ygl177w-Δ | S288C | Media: turbidostat growth in FPM medium Details: Relative growth score: 0.0035 | Pir P, et al. (2012) PMID:22244311 | |
| YGL177W | mutation frequency: increased | systematic mutation set | null Allele: ygl177w-Δ | S288C | Details: elevated spontaneous mutation rate, based on a mother enrichment program escaper frequency of >75%, and a 1.8-fold or greater increase in the CAN1 mutation rate; independent of replicative age | Novarina D, et al. (2020) PMID:31854076 | |
| YGL177W | replicative lifespan: increased | systematic mutation set | null Allele: ygl177w-Δ | S288C | Details: long-lived mutants, one standard deviation above the mean, were identified using an HTP sequencing-based yeast replicative lifespan screen (SEBYL), with pooled cells subject to four rounds of biotin-based sorting to enrich old vs young cells, followed by sequencing to ID mutants and abundance | Yu R, et al. (2021) PMID:33790287 | |
| YGL177W | resistance to chemicals: decreased | homozygous diploid, systematic mutation set | null Allele: ygl177w-Δ | S288C | 0.01 mM glycolaldehyde | Details: > 10% sensitivity relative to the wild-type (p<0.05) | Jayakody LN, et al. (2011) PMID:20960220 |
| YGL177W | resistance to chemicals: increased | systematic mutation set | null Allele: ygl177w-Δ | S288C | 5.1% (w/v), pH2.7 (S)-lactic acid | Kawahata M, et al. (2006) PMID:16911514 | |
| YGL177W | vacuolar morphology: abnormal | systematic mutation set screen all non-essential genes for inability to fragment vacuoles in response to salt addition | null Allele: ygl177w-Δ | S288C | 0.4 M sodium chloride | Details: small defect in vacuolar fragmentation | Michaillat L and Mayer A (2013) PMID:23383298 |
| YGL177W | viable | systematic mutation set | null Allele: ygl177w-Δ | S288C | Giaever G, et al. (2002) PMID:12140549 |
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
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