Gene Ontology Help

DCS1 decapping scavenger complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
m7G(5')pppN diphosphatase which degrades the 5-prime mRNA cap when the cap is no longer attached to the mRNA body but rather within short capped mRNA fragments that are generated from 3' to 5' mRNA decay. Releases m7GMP. Mononucleoside diphosphates (m7GDP and m3 2,2,7GDP) are not hydrolyzed by the complex, however mononucleoside triphosphates (m7GTP and m3 2,2,7GTP) are, demonstrating the importance of a triphosphate chain for DCS1 hydrolytic activity. Has a high binding affinity for m7GDP, which inhibits the complex, making this mononucleoside diphosphate a potential regulator of cap-dependent cellular processes.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

RNA binding, hydrolase activity, RNA catabolic process, catabolic process, nucleobase-containing compound catabolic process, cellular component