Gene Ontology Help

DCS1-DCS2 regulator of decapping scavenger complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
m7G(5')pppN diphosphatase with a kcat/KM value that is significantly lower than that of the Decapping Scavenger complex, DCS1 (CPX-1179) and has almost lost the preference for m7GpppG as a substrate shown by the homodimer. Degrades the 5' mRNA cap, releasing m7GMP, when the cap is no longer attached to the mRNA body but rather within short capped mRNA fragments that are generated from 3' to 5' mRNA decay. DCS2 is only expressed by the cell under conditions of diauxic stress, and the formation of this complex may allow the cell to change the distribution and relative activities of the mRNA decay pathways in the stationary phase cell.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

hydrolase activity, RNA catabolic process, catabolic process, nucleobase-containing compound catabolic process, organelle, P-body, intracellular membraneless organelle