Gene Ontology Help

Elongation Factor eEF1 complex, variant TEF4 Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Transports an aminoacylated-tRNA (aa-tRNA) to the ribosomal A-site during the elongation phase of protein synthesis. GTP bound to eEF1A (TEF1/2) is hydrolyzed upon codon-anticodon match between an aa-tRNA in the ribosomal RNA A-site and mRNA bound to the ribosome. Inactive eEF1A-GDP leaves the ribosome and must be recycled to eEF1A-GTP before binding another molecule of aa-tRNA. The guanine nucleotide exchange factor eEF1B catalyzes the exchange of GDP for GTP.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

GTPase activity, enzyme regulator activity, guanyl-nucleotide exchange factor activity, hydrolase activity, ion binding, translation factor activity, RNA binding, biosynthetic process, translational elongation, organelle, ribosome, intracellular membraneless organelle