GAL4-GAL80 transcription repressor complex

Primary Literature

Gencoglu M, et al. (2017) Measurement of In Vivo Protein Binding Affinities in a Signaling Network with Mass Spectrometry. ACS Synth Biol 6(7):1305-1314 PMID: 28333434
Egriboz O, et al. (2013) Self-association of the Gal4 inhibitor protein Gal80 is impaired by Gal3: evidence for a new mechanism in the GAL gene switch. Mol Cell Biol 33(18):3667-74 PMID: 23858060
Barnard E and Timson DJ (2011) The GAL genetic switch: visualisation of the interacting proteins by split-EGFP bimolecular fluorescence complementation. J Basic Microbiol 51(3):312-7 PMID: 21298679
Campbell RN, et al. (2011) Isolation of compensatory inhibitor domain mutants to novel activation domain variants using the split-ubiquitin screen. Yeast 28(8):569-78 PMID: 21732556
Li Y, et al. (2010) Multiple metabolic signals influence GAL gene activation by modulating the interaction of Gal80p with the transcriptional activator Gal4p. Mol Microbiol 78(2):414-28 PMID: 20979343
Li Y, et al. (2010) Alterations in the interaction between GAL4 and GAL80 effect regulation of the yeast GAL regulon mediated by the F box protein Dsg1. Curr Microbiol 61(3):210-6 PMID: 20135317
Jiang F, et al. (2009) Gene activation by dissociation of an inhibitor from a transcriptional activation domain. Mol Cell Biol 29(20):5604-10 PMID: 19651897
Kumar PR, et al. (2008) NADP regulates the yeast GAL induction system. Science 319(5866):1090-2 PMID: 18292341
Wightman R, et al. (2008) Localization and interaction of the proteins constituting the GAL genetic switch in Saccharomyces cerevisiae. Eukaryot Cell 7(12):2061-8 PMID: 18952899
Pilauri V, et al. (2005) Gal80 dimerization and the yeast GAL gene switch. Genetics 169(4):1903-14 PMID: 15695361
Sil AK, et al. (1999) The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP. Mol Cell Biol 19(11):7828-40 PMID: 10523671
Platt A and Reece RJ (1998) The yeast galactose genetic switch is mediated by the formation of a Gal4p-Gal80p-Gal3p complex. EMBO J 17(14):4086-91 PMID: 9670023
Wu Y, et al. (1996) Quantitation of putative activator-target affinities predicts transcriptional activating potentials. EMBO J 15(15):3951-63 PMID: 8670900
Melcher K and Johnston SA (1995) GAL4 interacts with TATA-binding protein and coactivators. Mol Cell Biol 15(5):2839-48 PMID: 7739564
Parthun MR and Jaehning JA (1992) A transcriptionally active form of GAL4 is phosphorylated and associated with GAL80. Mol Cell Biol 12(11):4981-7 PMID: 1406674
Yun SJ, et al. (1991) Purification and characterization of the yeast negative regulatory protein GAL80. J Biol Chem 266(2):693-7 PMID: 1985957
- SGD Paper
- PubMed

Additional Literature

Dugan A, et al. (2016) Discovery of Enzymatic Targets of Transcriptional Activators via in Vivo Covalent Chemical Capture. J Am Chem Soc 138(38):12629-35 PMID: 27611834

Das Adhikari AK, et al. (2014) Perturbation of the interaction between Gal4p and Gal80p of the Saccharomyces cerevisiae GAL switch results in altered responses to galactose and glucose. Mol Microbiol 94(1):202-17 PMID: 25135592

Dube DH, et al. (2010) A two-hybrid assay to study protein interactions within the secretory pathway. PLoS One 5(12):e15648 PMID: 21209940

Melcher K (2005) Mutational hypersensitivity of a gene regulatory protein: Saccharomyces cerevisiae Gal80p. Genetics 171(2):469-76 PMID: 15998719

Hertveldt K, et al. (2003) Identification of Gal80p-interacting proteins by Saccharomyces cerevisiae whole genome phage display. Gene 307:141-9 PMID: 12706896

Ansari AZ, et al. (2002) Transcriptional activating regions target a cyclin-dependent kinase. Proc Natl Acad Sci U S A 99(23):14706-9 PMID: 12417740

Chang C, et al. (2001) The Gal4 activation domain binds Sug2 protein, a proteasome component, in vivo and in vitro. J Biol Chem 276(33):30956-63 PMID: 11418596

Han Y and Kodadek T (2000) Peptides selected to bind the Gal80 repressor are potent transcriptional activation domains in yeast. J Biol Chem 275(20):14979-84 PMID: 10809742

Melcher K (2000) The strength of acidic activation domains correlates with their affinity for both transcriptional and non-transcriptional proteins. J Mol Biol 301(5):1097-112 PMID: 10966808

Marsolier MC, et al. (1997) A RNA polymerase III-based two-hybrid system to study RNA polymerase II transcriptional regulators. J Mol Biol 268(2):243-9 PMID: 9159467

Lue NF, et al. (1987) Interaction of GAL4 and GAL80 gene regulatory proteins in vitro. Mol Cell Biol 7(10):3446-51 PMID: 3316976

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GAL4-GAL80 transcription repressor complex Literature

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