Gene Ontology Help

TRM9-TRM112 methyltransferase complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
S-adenosylmethionine-dependent methyltransferase involved in the formation of mcm5(s2)U (5-methoxycarbonylmethyl(2-thio)uridine) modifications at position 34 from the anticodon loop of some tRNAs. This modification is present at the wobble position of tRNAArg(UCU), tRNAGly(UCC), tRNALys(UUU), tRNAGln(UUG) and tRNAGlu(UUC). Modifications in the anticodon loop of tRNAs are known to influence the translation rate and fidelity of decoding.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

RNA binding, methyltransferase activity, transferase activity, RNA modification, tRNA metabolic process, tRNA processing