Gene Ontology Help

HDA1 histone deacetylase complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Class II histone deacetylase, recruited to specific promoter loci through sequence-specific DNA-binding proteins, for example the TUP1 repressor (P16649), and subsequently precisely modifies adjacent nucleosomes at the lysine residues of histones H2B and H3 to repress transcription. Also deacetylates the N-terminal tails of the histones via a nonspecific DNA-binding mechanism.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

DNA binding, biological process