SLX1-SLX4 structure-specific endonuclease complex

Primary Literature

Xu X, et al. (2021) Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex. Nucleic Acids Res 49(13):7740-7752 PMID: 34181713
Balint A, et al. (2015) Assembly of Slx4 signaling complexes behind DNA replication forks. EMBO J 34(16):2182-97 PMID: 26113155
Roberts TM, et al. (2006) Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Mol Biol Cell 17(1):539-48 PMID: 16267268
Fricke WM and Brill SJ (2003) Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3. Genes Dev 17(14):1768-78 PMID: 12832395
Mullen JR, et al. (2001) Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Genetics 157(1):103-18 PMID: 11139495

Additional Literature

Wan B, et al. (2019) Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107. Mol Cell 75(2):238-251.e5 PMID: 31348879

Dibitetto D, et al. (2016) Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks. Nucleic Acids Res 44(2):669-82 PMID: 26490958

Thu HP, et al. (2015) A physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repair. Nucleic Acids Res 43(3):1684-99 PMID: 25628354

Gritenaite D, et al. (2014) A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication. Genes Dev 28(14):1604-19 PMID: 25030699

Pardo B and Aguilera A (2012) Complex chromosomal rearrangements mediated by break-induced replication involve structure-selective endonucleases. PLoS Genet 8(9):e1002979 PMID: 23071463

Li F, et al. (2008) Microarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediates. Mol Cell 30(3):325-35 PMID: 18471978

Kaliraman V and Brill SJ (2002) Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae. Curr Genet 41(6):389-400 PMID: 12228808

Reviews

Jia N, et al. (2025) Engineering recombination machinery facilitates the construction of yeast cell factories. FEMS Yeast Res 25 PMID: 41231539

Börner GV, et al. (2023) Meiosis in budding yeast. Genetics 225(2) PMID: 37616582

Putnam CD and Kolodner RD (2017) Pathways and Mechanisms that Prevent Genome Instability in <i>Saccharomyces cerevisiae</i>. Genetics 206(3):1187-1225 PMID: 28684602

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Reviews

SLX1-SLX4 structure-specific endonuclease complex Literature

Primary Literature

Additional Literature