Mitotic checkpoint complex, MAD1-MAD2-BUB1-BUB3 subcomplex

Primary Literature

Aravamudhan P, et al. (2016) Dual mechanisms regulate the recruitment of spindle assembly checkpoint proteins to the budding yeast kinetochore. Mol Biol Cell 27(22):3405-3417 PMID: 27170178
Mora-Santos MD, et al. (2016) Bub3-Bub1 Binding to Spc7/KNL1 Toggles the Spindle Checkpoint Switch by Licensing the Interaction of Bub1 with Mad1-Mad2. Curr Biol 26(19):2642-2650 PMID: 27618268
London N and Biggins S (2014) Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint. Genes Dev 28(2):140-52 PMID: 24402315
Primorac I, et al. (2013) Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling. Elife 2:e01030 PMID: 24066227
Haase J, et al. (2012) Bub1 kinase and Sgo1 modulate pericentric chromatin in response to altered microtubule dynamics. Curr Biol 22(6):471-81 PMID: 22365852
Lara-Gonzalez P, et al. (2012) The spindle assembly checkpoint. Curr Biol 22(22):R966-80 PMID: 23174302
Andrews CA, et al. (2006) A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin. Genes Dev 20(9):1162-74 PMID: 16651657
Kastenmayer JP, et al. (2005) The C-terminal half of Saccharomyces cerevisiae Mad1p mediates spindle checkpoint function, chromosome transmission fidelity and CEN association. Genetics 170(2):509-17 PMID: 15802513
Kerscher O, et al. (2003) Recognizing chromosomes in trouble: association of the spindle checkpoint protein Bub3p with altered kinetochores and a unique defective centromere. Mol Cell Biol 23(18):6406-18 PMID: 12944469
Warren CD, et al. (2002) Distinct chromosome segregation roles for spindle checkpoint proteins. Mol Biol Cell 13(9):3029-41 PMID: 12221113
Fraschini R, et al. (2001) Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO J 20(23):6648-59 PMID: 11726501
Brady DM and Hardwick KG (2000) Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function. Curr Biol 10(11):675-8 PMID: 10837255
Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82 PMID: 10704439
Roberts BT, et al. (1994) The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase. Mol Cell Biol 14(12):8282-91 PMID: 7969164

Additional Literature

Scott RJ, et al. (2009) The nuclear export factor Xpo1p targets Mad1p to kinetochores in yeast. J Cell Biol 184(1):21-9 PMID: 19139260

Fernius J and Hardwick KG (2007) Bub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis. PLoS Genet 3(11):e213 PMID: 18081426

Riedel CG, et al. (2006) Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Nature 441(7089):53-61 PMID: 16541024

Kiburz BM, et al. (2005) The core centromere and Sgo1 establish a 50-kb cohesin-protected domain around centromeres during meiosis I. Genes Dev 19(24):3017-30 PMID: 16357219

Hwang LH, et al. (1998) Budding yeast Cdc20: a target of the spindle checkpoint. Science 279(5353):1041-4 PMID: 9461437

Hoyt MA, et al. (1991) S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell 66(3):507-17 PMID: 1651171

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Mitotic checkpoint complex, MAD1-MAD2-BUB1-BUB3 subcomplex Literature

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