Primary Literature
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- Kaur U, et al. (2025) Autoinhibition imposed by a large conformational switch of INO80 regulates nucleosome positioning. Science 389(6757):eadr3831 PMID: 40674492
- Shukla S, et al. (2025) Conformational switching of Arp5 subunit regulates INO80 chromatin remodeling. Nucleic Acids Res 53(2) PMID: 39676660
- Abrhámová K, et al. (2024) Truncating the spliceosomal 'rope protein' Prp45 results in Htz1 dependent phenotypes. RNA Biol 21(1):1-17 PMID: 38711165
- Hurst V, et al. (2024) Loss of cytoplasmic actin filaments raises nuclear actin levels to drive INO80C-dependent chromosome fragmentation. Nat Commun 15(1):9910 PMID: 39548059
- Shimada K, et al. (2024) TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events. Nat Commun 15(1):9908 PMID: 39548071
- Yuan B, et al. (2024) The chromatin remodeler Ino80 regulates yeast stress tolerance and cell metabolism through modulating nitrogen catabolite repression. Int J Biol Macromol 258(Pt 2):129041 PMID: 38154715
- Chacin E, et al. (2023) Establishment and function of chromatin organization at replication origins. Nature 616(7958):836-842 PMID: 37020028
- Ólafsson G, et al. (2023) Humanization reveals pervasive incompatibility of yeast and human kinetochore components. G3 (Bethesda) 14(1) PMID: 37962556
- Sokolova V, et al. (2023) DNA-translocation-independent role of INO80 remodeler in DNA damage repairs. J Biol Chem 299(10):105245 PMID: 37696438
- Wu H, et al. (2023) Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science 381(6655):319-324 PMID: 37384669
- Hsieh LJ, et al. (2022) A hexasome is the preferred substrate for the INO80 chromatin remodeling complex, allowing versatility of function. Mol Cell 82(11):2098-2112.e4 PMID: 35597239
- Hurst V, et al. (2021) A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress. EMBO J 40(21):e108439 PMID: 34569643
- Cheblal A, et al. (2020) DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement. Mol Cell 80(2):311-326.e4 PMID: 32970994
- Qiu H, et al. (2020) Chromatin remodeler Ino80C acts independently of H2A.Z to evict promoter nucleosomes and stimulate transcription of highly expressed genes in yeast. Nucleic Acids Res 48(15):8408-8430 PMID: 32663283
- Topal S, et al. (2020) INO80C Remodeler Maintains Genomic Stability by Preventing Promiscuous Transcription at Replication Origins. Cell Rep 32(10):108106 PMID: 32905765
- Beckwith SL, et al. (2018) The INO80 chromatin remodeler sustains metabolic stability by promoting TOR signaling and regulating histone acetylation. PLoS Genet 14(2):e1007216 PMID: 29462149
- Brahma S, et al. (2018) The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling. Nat Commun 9(1):3309 PMID: 30120252
- Cutler S, et al. (2018) Chromatin Remodeling Factors Isw2 and Ino80 Regulate Chromatin, Replication, and Copy Number of the <i>Saccharomyces cerevisiae</i> Ribosomal DNA Locus. Genetics 210(4):1543-1556 PMID: 30355728
- Zhou CY, et al. (2018) The Yeast INO80 Complex Operates as a Tunable DNA Length-Sensitive Switch to Regulate Nucleosome Sliding. Mol Cell 69(4):677-688.e9 PMID: 29452642
- Klopf E, et al. (2017) INO80 represses osmostress induced gene expression by resetting promoter proximal nucleosomes. Nucleic Acids Res 45(7):3752-3766 PMID: 28025392
- Kapoor P, et al. (2015) Phosphorylation-Dependent Enhancement of Rad53 Kinase Activity through the INO80 Chromatin Remodeling Complex. Mol Cell 58(5):863-9 PMID: 25959398
- Watanabe S, et al. (2015) Structural analyses of the chromatin remodelling enzymes INO80-C and SWR-C. Nat Commun 6:7108 PMID: 25964121
- Yao W, et al. (2015) Assembly of the Arp5 (Actin-related Protein) Subunit Involved in Distinct INO80 Chromatin Remodeling Activities. J Biol Chem 290(42):25700-9 PMID: 26306040
- Vassileva I, et al. (2014) The mammalian INO80 chromatin remodeling complex is required for replication stress recovery. Nucleic Acids Res 42(14):9074-86 PMID: 25016522
- Hu Y, et al. (2013) Telomerase-null survivor screening identifies novel telomere recombination regulators. PLoS Genet 9(1):e1003208 PMID: 23390378
- Kapoor P, et al. (2013) Evidence for monomeric actin function in INO80 chromatin remodeling. Nat Struct Mol Biol 20(4):426-32 PMID: 23524535
- Tosi A, et al. (2013) Structure and subunit topology of the INO80 chromatin remodeler and its nucleosome complex. Cell 154(6):1207-19 PMID: 24034245
- Wood TJ, et al. (2013) Mutations in non-acid patch residues disrupt H2A.Z's association with chromatin through multiple mechanisms. PLoS One 8(10):e76394 PMID: 24098487
- Chambers AL, et al. (2012) The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres. Genes Dev 26(23):2590-603 PMID: 23207916
- Kato D, et al. (2012) Phosphorylation of human INO80 is involved in DNA damage tolerance. Biochem Biophys Res Commun 417(1):433-8 PMID: 22166198
- Saravanan M, et al. (2012) Interactions between the nucleosome histone core and Arp8 in the INO80 chromatin remodeling complex. Proc Natl Acad Sci U S A 109(51):20883-8 PMID: 23213201
- Jiang Y, et al. (2010) INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway. Proc Natl Acad Sci U S A 107(40):17274-9 PMID: 20855601
- Falbo KB, et al. (2009) Involvement of a chromatin remodeling complex in damage tolerance during DNA replication. Nat Struct Mol Biol 16(11):1167-72 PMID: 19855395
- Hannum G, et al. (2009) Genome-wide association data reveal a global map of genetic interactions among protein complexes. PLoS Genet 5(12):e1000782 PMID: 20041197
- Shimada K, et al. (2008) Ino80 chromatin remodeling complex promotes recovery of stalled replication forks. Curr Biol 18(8):566-75 PMID: 18406137
- Bao Y and Shen X (2007) INO80 subfamily of chromatin remodeling complexes. Mutat Res 618(1-2):18-29 PMID: 17316710
- Kawashima S, et al. (2007) The INO80 complex is required for damage-induced recombination. Biochem Biophys Res Commun 355(3):835-41 PMID: 17320816
- Yu EY, et al. (2007) Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex. Mol Cell Biol 27(16):5639-49 PMID: 17562861
- Javaheri A, et al. (2006) Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling. Proc Natl Acad Sci U S A 103(37):13771-6 PMID: 16940359
- Jin J, et al. (2005) A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. J Biol Chem 280(50):41207-12 PMID: 16230350
- Morrison AJ, et al. (2004) INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell 119(6):767-75 PMID: 15607974
- van Attikum H, et al. (2004) Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell 119(6):777-88 PMID: 15607975
- Shen X, et al. (2000) A chromatin remodelling complex involved in transcription and DNA processing. Nature 406(6795):541-4 PMID: 10952318