Gene Ontology Help

COMPASS complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Histone methyltransferase that catalyzes methylation of Lys-4 of histone H3 and thus controls the silencing of telomeric regions. SWD1, SWD3, and SET1 constitute a core of the complex, and the absence of any of these subunits abolishes methylation of lysine 4 on histone H3. Subunits BRE2 and SDC1 are essential for trimethylation and important for mono- and dimethylation by the COMPASS complex. SPP1 is important for trimethylation, while SHG1 plays a minor role in trimethylation.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

methyltransferase activity, transferase activity, chromatin organization, histone modification, peptidyl-amino acid modification, protein alkylation, nucleus, organelle, Set1C/COMPASS complex