Gene Ontology Help

Nem1-Spo7 phosphatase complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Phosphatase complex with an essential role in formation of a spherical nucleus and meiotic division. Dephosphorylates PAH1 (P32567), a critical factor in coordinating phospholipid biosynthesis at the nuclear/ER membrane with nuclear growth during the cell cycle. NEM1-SPO7-mediated regulation of membrane biogenesis is required to promote mitophagy.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

hydrolase activity, phosphatase activity, membrane organization