Gene Ontology Help

Dynactin complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Required for intracellular transport by dynein by localizing cytoplasmic dynein to its proper intracellular cargo and modulating dynein motor activity. Dynactin increases the run length of single dynein motors, but does not alter the directionality of dynein movement. Required for the spindle translocation late in anaphase and is involved in a cell wall synthesis checkpoint.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

cytoskeleton organization, cytoskeleton, organelle, intracellular non-membrane-bounded organelle