Gene Ontology Help

DNA ligase IV complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
DNA ligase which catalyses the final ligation step in the non-homologous end-joining DNA repair pathway. Ligates DNA strands to restore the continuity of the chromosome in non-homologous end joining DNA double-strand break repair. Interacts with the Ku70:Ku80 (CPX-1732) and MRX CPX-1872) complexes.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

nucleotidyltransferase activity, transferase activity, DNA damage response, DNA metabolic process, DNA repair, response to stress, nucleus, organelle