Gene Ontology Help

TREX-2 transcription-export complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Couples SAGA (CPX-656)-dependent gene expression and transcription elongation to mRNA export at the inner side of the nuclear pore complex (NPC, CPX-824). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins NUP1 (P20676) and NUP60 (P39705) and facilitates the repositioning and association of actively transcribing genes with nuclear pores (gene gating). Provides a feedback mechanism for the control of transcription and the preservation of genetic integrity of transcribed DNA regions.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

nuclear transport, nucleobase-containing compound transport, nucleocytoplasmic transport, transport