Primary Literature
TEXT HERE
- Kamada Y, et al. (2024) Structure-based engineering of Tor complexes reveals that two types of yeast TORC1 produce distinct phenotypes. J Cell Sci 137(4) PMID: 38415789
- Shimada K, et al. (2024) TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events. Nat Commun 15(1):9908 PMID: 39548071
- Gutiérrez-Santiago F, et al. (2022) A High-Copy Suppressor Screen Reveals a Broad Role of Prefoldin-like Bud27 in the TOR Signaling Pathway in <i>Saccharomyces cerevisiae</i>. Genes (Basel) 13(5) PMID: 35627133
- Ishino Y, et al. (2022) Regulation of sphingolipid biosynthesis in the endoplasmic reticulum via signals from the plasma membrane in budding yeast. FEBS J 289(2):457-472 PMID: 34492164
- Nomura W, et al. (2022) Roles of phosphatidylserine and phospholipase C in the activation of TOR complex 2 signaling in Saccharomyces cerevisiae. J Cell Sci 135(17) PMID: 35912799
- Tsverov J, et al. (2022) Identification of defined structural elements within TOR2 kinase required for TOR complex 2 assembly and function in <i>Saccharomyces cerevisiae</i>. Mol Biol Cell 33(5):ar44 PMID: 35293776
- Furukawa K, et al. (2021) Mitophagy regulation mediated by the Far complex in yeast. Autophagy 17(4):1042-1043 PMID: 33530805
- Galez HA, et al. (2021) Phosphorylation of mRNA-Binding Proteins Puf1 and Puf2 by TORC2-Activated Protein Kinase Ypk1 Alleviates Their Repressive Effects. Membranes (Basel) 11(7) PMID: 34209236
- Kakhlon O (2021) Casting iron into the cell fate mold. Biochem J 478(10):1879-1883 PMID: 34029365
- Toyoda Y and Saitoh S (2021) Fission Yeast TORC2 Signaling Pathway Ensures Cell Proliferation under Glucose-Limited, Nitrogen-Replete Conditions. Biomolecules 11(10) PMID: 34680098
- Alcaide-Gavilán M, et al. (2020) Conserved Ark1-related kinases function in a TORC2 signaling network. Mol Biol Cell 31(18):2057-2069 PMID: 32614710
- Innokentev A, et al. (2020) Association and dissociation between the mitochondrial Far complex and Atg32 regulate mitophagy. Elife 9 PMID: 33317697
- Knudsen JR, et al. (2020) Growth Factor-Dependent and -Independent Activation of mTORC2. Trends Endocrinol Metab 31(1):13-24 PMID: 31699566
- Maiese K (2020) Nicotinamide: Oversight of Metabolic Dysfunction Through SIRT1, mTOR, and Clock Genes. Curr Neurovasc Res 17(5):765-783 PMID: 33183203
- Riggi M, et al. (2020) The flipside of the TOR coin - TORC2 and plasma membrane homeostasis at a glance. J Cell Sci 133(9) PMID: 32393676
- Schmidt O, et al. (2020) TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast. J Biol Chem 295(34):12028-12044 PMID: 32611771
- Tafur L, et al. (2020) Structural Insights into TOR Signaling. Genes (Basel) 11(8) PMID: 32759652
- Topolska M, et al. (2020) TORC2-Dependent Ypk1-Mediated Phosphorylation of Lam2/Ltc4 Disrupts Its Association with the β-Propeller Protein Laf1 at Endoplasmic Reticulum-Plasma Membrane Contact Sites in the Yeast <i>Saccharomyces cerevisiae</i>. Biomolecules 10(12) PMID: 33255682
- Athanasopoulos A, et al. (2019) Fungal plasma membrane domains. FEMS Microbiol Rev 43(6):642-673 PMID: 31504467
- Babst M (2019) Eisosomes at the intersection of TORC1 and TORC2 regulation. Traffic 20(8):543-551 PMID: 31038844
- Dereli Eke E, et al. (2019) Identification of Novel Components of Target-of-Rapamycin Signaling Pathway by Network-Based Multi-Omics Integrative Analysis. OMICS 23(5):274-284 PMID: 30985253
- Leitao RM, et al. (2019) A Conserved PP2A Regulatory Subunit Enforces Proportional Relationships Between Cell Size and Growth Rate. Genetics 213(2):517-528 PMID: 31488515
- Locke MN and Thorner J (2019) Rab5 GTPases are required for optimal TORC2 function. J Cell Biol 218(3):961-976 PMID: 30578283
- Locke MN and Thorner J (2019) Regulation of TORC2 function and localization by Rab5 GTPases in <i>Saccharomyces cerevisiae</i>. Cell Cycle 18(10):1084-1094 PMID: 31068077
- Martinez Marshall MN, et al. (2019) Analysis of the roles of phosphatidylinositol-4,5-<i>bis</i>phosphate and individual subunits in assembly, localization, and function of <i>Saccharomyces cerevisiae</i> target of rapamycin complex 2. Mol Biol Cell 30(12):1555-1574 PMID: 30969890
- Riggi M, et al. (2019) TORC2 controls endocytosis through plasma membrane tension. J Cell Biol 218(7):2265-2276 PMID: 31123183
- Ruan C, et al. (2019) Sin1-mediated mTOR signaling in cell growth, metabolism and immune response. Natl Sci Rev 6(6):1149-1162 PMID: 34691993
- Suda K, et al. (2019) TORC1 regulates autophagy induction in response to proteotoxic stress in yeast and human cells. Biochem Biophys Res Commun 511(2):434-439 PMID: 30797551
- Alcaide-Gavilán M, et al. (2018) Modulation of TORC2 Signaling by a Conserved Lkb1 Signaling Axis in Budding Yeast. Genetics 210(1):155-170 PMID: 29986907
- Bourgoint C, et al. (2018) Target of rapamycin complex 2-dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in <i>Saccharomyces cerevisiae</i>. J Biol Chem 293(31):12043-12053 PMID: 29895620
- Busto JV, et al. (2018) Lateral plasma membrane compartmentalization links protein function and turnover. EMBO J 37(16) PMID: 29976762
- Gournas C, et al. (2018) Conformation-dependent partitioning of yeast nutrient transporters into starvation-protective membrane domains. Proc Natl Acad Sci U S A 115(14):E3145-E3154 PMID: 29559531
- Hill A, et al. (2018) Redesigning TOR Kinase to Explore the Structural Basis for TORC1 and TORC2 Assembly. Biomolecules 8(2) PMID: 29865216
- Leskoske KL, et al. (2018) Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2. Genes Dev 32(23-24):1576-1590 PMID: 30478248
- Lucena R, et al. (2018) Cell Size and Growth Rate Are Modulated by TORC2-Dependent Signals. Curr Biol 28(2):196-210.e4 PMID: 29290562
- Martín R and Lopez-Aviles S (2018) Express yourself: how PP2A-B55<sup>Pab1</sup> helps TORC1 talk to TORC2. Curr Genet 64(1):43-51 PMID: 28643116
- Riggi M, et al. (2018) Decrease in plasma membrane tension triggers PtdIns(4,5)P<sub>2</sub> phase separation to inactivate TORC2. Nat Cell Biol 20(9):1043-1051 PMID: 30154550
- Rodríguez-Escudero I, et al. (2018) Heterologous mammalian Akt disrupts plasma membrane homeostasis by taking over TORC2 signaling in Saccharomyces cerevisiae. Sci Rep 8(1):7732 PMID: 29769614
- Roelants FM, et al. (2018) TOR complex 2-regulated protein kinase Ypk1 controls sterol distribution by inhibiting StARkin domain-containing proteins located at plasma membrane-endoplasmic reticulum contact sites. Mol Biol Cell 29(17):2128-2136 PMID: 29927351
- Gonzalez S and Rallis C (2017) The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth. Front Cell Dev Biol 5:61 PMID: 28638821
- Hatakeyama R, et al. (2017) Ypk1 and Ypk2 kinases maintain Rho1 at the plasma membrane by flippase-dependent lipid remodeling after membrane stresses. J Cell Sci 130(6):1169-1178 PMID: 28167678
- Karuppasamy M, et al. (2017) Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2. Nat Commun 8(1):1729 PMID: 29170376
- Leskoske KL, et al. (2017) The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites. Genetics 207(1):179-195 PMID: 28739659
- Martín R, et al. (2017) A PP2A-B55-Mediated Crosstalk between TORC1 and TORC2 Regulates the Differentiation Response in Fission Yeast. Curr Biol 27(2):175-188 PMID: 28041796
- Murley A, et al. (2017) Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling. J Cell Biol 216(9):2679-2689 PMID: 28774891
- Prouteau M, et al. (2017) TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity. Nature 550(7675):265-269 PMID: 28976958
- Roelants FM, et al. (2017) TOR Complex 2-Regulated Protein Kinase Fpk1 Stimulates Endocytosis via Inhibition of Ark1/Prk1-Related Protein Kinase Akl1 in Saccharomyces cerevisiae. Mol Cell Biol 37(7) PMID: 28069741
- Roelants FM, et al. (2017) The TORC2-Dependent Signaling Network in the Yeast Saccharomyces cerevisiae. Biomolecules 7(3) PMID: 28872598
- Tatebe H and Shiozaki K (2017) Evolutionary Conservation of the Components in the TOR Signaling Pathways. Biomolecules 7(4) PMID: 29104218
- Vlahakis A, et al. (2017) Stress-response transcription factors Msn2 and Msn4 couple TORC2-Ypk1 signaling and mitochondrial respiration to ATG8 gene expression and autophagy. Autophagy 13(11):1804-1812 PMID: 29198169
- Baretić D, et al. (2016) Tor forms a dimer through an N-terminal helical solenoid with a complex topology. Nat Commun 7:11016 PMID: 27072897
- Guerreiro JF, et al. (2016) Sphingolipid biosynthesis upregulation by TOR complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stress. Biochem J 473(23):4311-4325 PMID: 27671892
- Maiese K (2016) Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOR. Neural Regen Res 11(3):372-85 PMID: 27127460
- Maiese K (2016) Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life Expectancy. Curr Neurovasc Res 13(4):329-340 PMID: 27488211
- Omnus DJ, et al. (2016) Phosphoinositide kinase signaling controls ER-PM cross-talk. Mol Biol Cell 27(7):1170-80 PMID: 26864629
- Teixeira V and Costa V (2016) Unraveling the role of the Target of Rapamycin signaling in sphingolipid metabolism. Prog Lipid Res 61:109-33 PMID: 26703187
- Vlahakis A, et al. (2016) Calcium channel regulator Mid1 links TORC2-mediated changes in mitochondrial respiration to autophagy. J Cell Biol 215(6):779-788 PMID: 27899413
- Weisman R (2016) Target of Rapamycin (TOR) Regulates Growth in Response to Nutritional Signals. Microbiol Spectr 4(5) PMID: 27763256
- Yerlikaya S, et al. (2016) TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae. Mol Biol Cell 27(2):397-409 PMID: 26582391
- Bartlett K, et al. (2015) TORC2 and eisosomes are spatially interdependent, requiring optimal level of phosphatidylinositol 4, 5-bisphosphate for their integrity. J Biosci 40(2):299-311 PMID: 25963258
- Gaubitz C, et al. (2015) Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2. Mol Cell 58(6):977-88 PMID: 26028537
- Maegawa K, et al. (2015) Evolutionary conservation of TORC1 components, TOR, Raptor, and LST8, between rice and yeast. Mol Genet Genomics 290(5):2019-30 PMID: 25956502
- Muir A, et al. (2015) Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress. Elife 4 PMID: 26274562
- Nomura W and Inoue Y (2015) Methylglyoxal activates the target of rapamycin complex 2-protein kinase C signaling pathway in Saccharomyces cerevisiae. Mol Cell Biol 35(7):1269-80 PMID: 25624345
- Rispal D, et al. (2015) Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways. J Biol Chem 290(24):14963-78 PMID: 25882841
- Yasuda K, et al. (2015) Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS One 10(11):e0142943 PMID: 26600389
- Bartlett K and Kim K (2014) Insight into Tor2, a budding yeast microdomain protein. Eur J Cell Biol 93(3):87-97 PMID: 24629393
- Gordon BS, et al. (2014) RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells. Cell Signal 26(3):461-7 PMID: 24316235
- Kennedy MA, et al. (2014) A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast. PLoS Genet 10(1):e1004010 PMID: 24465216
- Muir A, et al. (2014) TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids. Elife 3 PMID: 25279700
- Niles BJ and Powers T (2014) TOR complex 2-Ypk1 signaling regulates actin polarization via reactive oxygen species. Mol Biol Cell 25(24):3962-72 PMID: 25253719
- Niles BJ, et al. (2014) TOR complex 2-Ypk1 signaling maintains sphingolipid homeostasis by sensing and regulating ROS accumulation. Cell Rep 6(3):541-52 PMID: 24462291
- Vlahakis A and Powers T (2014) A role for TOR complex 2 signaling in promoting autophagy. Autophagy 10(11):2085-6 PMID: 25426890
- Vlahakis A, et al. (2014) TOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy. Proc Natl Acad Sci U S A 111(29):10586-91 PMID: 25002487
- Weisman R, et al. (2014) TORC2-a new player in genome stability. EMBO Mol Med 6(8):995-1002 PMID: 24992933
- Gururaj C, et al. (2013) Orm proteins integrate multiple signals to maintain sphingolipid homeostasis. J Biol Chem 288(28):20453-63 PMID: 23737533
- Kliegman JI, et al. (2013) Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae. Cell Rep 5(6):1725-36 PMID: 24360963
- Pracheil T and Liu Z (2013) Tiered assembly of the yeast Far3-7-8-9-10-11 complex at the endoplasmic reticulum. J Biol Chem 288(23):16986-16997 PMID: 23625923
- Shimada K, et al. (2013) TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks. Mol Cell 51(6):829-39 PMID: 24035500
- Lee YJ, et al. (2012) Reciprocal phosphorylation of yeast glycerol-3-phosphate dehydrogenases in adaptation to distinct types of stress. Mol Cell Biol 32(22):4705-17 PMID: 22988299
- Liao HC and Chen MY (2012) Target of rapamycin complex 2 signals to downstream effector yeast protein kinase 2 (Ypk2) through adheres-voraciously-to-target-of-rapamycin-2 protein 1 (Avo1) in Saccharomyces cerevisiae. J Biol Chem 287(9):6089-99 PMID: 22207764
- Liu Q, et al. (2012) Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae. ACS Chem Biol 7(6):982-7 PMID: 22496512
- Niles BJ and Powers T (2012) Plasma membrane proteins Slm1 and Slm2 mediate activation of the AGC kinase Ypk1 by TORC2 and sphingolipids in S. cerevisiae. Cell Cycle 11(20):3745-9 PMID: 22895050
- Niles BJ, et al. (2012) Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2. Proc Natl Acad Sci U S A 109(5):1536-41 PMID: 22307609
- Pagán-Mercado G, et al. (2012) Functional and genetic interactions of TOR in the budding yeast Saccharomyces cerevisiae with myosin type II-deficiency (myo1Δ). BMC Cell Biol 13:13 PMID: 22646158
- Pan D and Matsuura Y (2012) Structures of the pleckstrin homology domain of Saccharomyces cerevisiae Avo1 and its human orthologue Sin1, an essential subunit of TOR complex 2. Acta Crystallogr Sect F Struct Biol Cryst Commun 68(Pt 4):386-92 PMID: 22505404
- Pracheil T, et al. (2012) TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae. Genetics 190(4):1325-39 PMID: 22298706
- Kim J and Guan KL (2011) Amino acid signaling in TOR activation. Annu Rev Biochem 80:1001-32 PMID: 21548787
- Roelants FM, et al. (2011) Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(48):19222-7 PMID: 22080611
- Ungar L, et al. (2011) Tor complex 1 controls telomere length by affecting the level of Ku. Curr Biol 21(24):2115-20 PMID: 22169538
- Wei Y and Zheng XF (2011) Nutritional control of cell growth via TOR signaling in budding yeast. Methods Mol Biol 759:307-19 PMID: 21863495
- Fonslow BR, et al. (2010) Native capillary isoelectric focusing for the separation of protein complex isoforms and subcomplexes. Anal Chem 82(15):6643-51 PMID: 20614870
- Limson MV and Sweder KS (2010) Rapamycin inhibits yeast nucleotide excision repair independently of tor kinases. Toxicol Sci 113(1):77-84 PMID: 19805410
- Michelot A, et al. (2010) Reconstitution and protein composition analysis of endocytic actin patches. Curr Biol 20(21):1890-9 PMID: 21035341
- Takai H, et al. (2010) Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes. Genes Dev 24(18):2019-30 PMID: 20801936
- Berchtold D and Walther TC (2009) TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain. Mol Biol Cell 20(5):1565-75 PMID: 19144819
- Cybulski N and Hall MN (2009) TOR complex 2: a signaling pathway of its own. Trends Biochem Sci 34(12):620-7 PMID: 19875293
- Meyer V, et al. (2009) Reconstruction of signaling networks regulating fungal morphogenesis by transcriptomics. Eukaryot Cell 8(11):1677-91 PMID: 19749177
- Soulard A, et al. (2009) TOR signaling in invertebrates. Curr Opin Cell Biol 21(6):825-36 PMID: 19767189
- Aronova S, et al. (2008) Regulation of ceramide biosynthesis by TOR complex 2. Cell Metab 7(2):148-58 PMID: 18249174
- Díaz-Troya S, et al. (2008) Target of rapamycin and LST8 proteins associate with membranes from the endoplasmic reticulum in the unicellular green alga Chlamydomonas reinhardtii. Eukaryot Cell 7(2):212-22 PMID: 18039939
- Dickson RC (2008) Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast. J Lipid Res 49(5):909-21 PMID: 18296751
- Dickson RC (2008) More chores for TOR: de novo ceramide synthesis. Cell Metab 7(2):99-100 PMID: 18249168
- Facchinetti V, et al. (2008) The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. EMBO J 27(14):1932-43 PMID: 18566586
- Ho HL, et al. (2008) Involvement of Saccharomyces cerevisiae Avo3p/Tsc11p in maintaining TOR complex 2 integrity and coupling to downstream signaling. Eukaryot Cell 7(8):1328-43 PMID: 18552287
- Jacinto E (2008) What controls TOR? IUBMB Life 60(8):483-96 PMID: 18493947
- Jacinto E and Lorberg A (2008) TOR regulation of AGC kinases in yeast and mammals. Biochem J 410(1):19-37 PMID: 18215152
- Liao XH, et al. (2008) Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism. Amino Acids 35(4):761-70 PMID: 18651095
- Adami A, et al. (2007) Structure of TOR and its complex with KOG1. Mol Cell 27(3):509-16 PMID: 17679098
- Aronova S, et al. (2007) Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae. Mol Biol Cell 18(8):2779-94 PMID: 17507646
- Daquinag A, et al. (2007) The yeast PH domain proteins Slm1 and Slm2 are targets of sphingolipid signaling during the response to heat stress. Mol Cell Biol 27(2):633-50 PMID: 17101780
- Urban J, et al. (2007) Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. Mol Cell 26(5):663-74 PMID: 17560372
- Bultynck G, et al. (2006) Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease. Mol Cell Biol 26(12):4729-45 PMID: 16738335
- De Virgilio C and Loewith R (2006) Cell growth control: little eukaryotes make big contributions. Oncogene 25(48):6392-415 PMID: 17041625
- Inoki K and Guan KL (2006) Complexity of the TOR signaling network. Trends Cell Biol 16(4):206-12 PMID: 16516475
- Mulet JM, et al. (2006) Mutual antagonism of target of rapamycin and calcineurin signaling. J Biol Chem 281(44):33000-7 PMID: 16959779
- Reinke A, et al. (2006) Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p. J Biol Chem 281(42):31616-26 PMID: 16923813
- Takahara T, et al. (2006) Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region. J Biol Chem 281(39):28605-14 PMID: 16870609
- Araki T, et al. (2005) LAS24/KOG1, a component of the TOR complex 1 (TORC1), is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast. Genes Genet Syst 80(5):325-43 PMID: 16394584
- Fadri M, et al. (2005) The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2. Mol Biol Cell 16(4):1883-900 PMID: 15689497
- Ho HL, et al. (2005) Saccharomyces cerevisiaeTSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex. Curr Genet 47(5):273-88 PMID: 15809876
- Kamada Y, et al. (2005) Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization. Mol Cell Biol 25(16):7239-48 PMID: 16055732
- Lee S, et al. (2005) TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium. Mol Biol Cell 16(10):4572-83 PMID: 16079174
- Martin DE and Hall MN (2005) The expanding TOR signaling network. Curr Opin Cell Biol 17(2):158-66 PMID: 15780592
- Wullschleger S, et al. (2005) Molecular organization of target of rapamycin complex 2. J Biol Chem 280(35):30697-704 PMID: 16002396
- Audhya A, et al. (2004) Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton. EMBO J 23(19):3747-57 PMID: 15372071
- Jacinto E, et al. (2004) Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol 6(11):1122-8 PMID: 15467718
- Reinke A, et al. (2004) TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem 279(15):14752-62 PMID: 14736892
- Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 PMID: 12408816