Primary Literature
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- Bae SJ, et al. (2021) High-yield production of (R)-acetoin in Saccharomyces cerevisiae by deleting genes for NAD(P)H-dependent ketone reductases producing meso-2,3-butanediol and 2,3-dimethylglycerate. Metab Eng 66:68-78 PMID: 33845171
- Cui DY, et al. (2020) Increasing Yield of 2,3,5,6-Tetramethylpyrazine in Baijiu Through <i>Saccharomyces cerevisiae</i> Metabolic Engineering. Front Microbiol 11:596306 PMID: 33324376
- Lonhienne T, et al. (2020) Structures of fungal and plant acetohydroxyacid synthases. Nature 586(7828):317-321 PMID: 32640464
- Park SH and Hahn JS (2019) Development of an efficient cytosolic isobutanol production pathway in Saccharomyces cerevisiae by optimizing copy numbers and expression of the pathway genes based on the toxic effect of α-acetolactate. Sci Rep 9(1):3996 PMID: 30850698
- Wess J, et al. (2019) Improving isobutanol production with the yeast <i>Saccharomyces cerevisiae</i> by successively blocking competing metabolic pathways as well as ethanol and glycerol formation. Biotechnol Biofuels 12:173 PMID: 31303893
- Ishii J, et al. (2018) A pyruvate carbon flux tugging strategy for increasing 2,3-butanediol production and reducing ethanol subgeneration in the yeast <i>Saccharomyces cerevisiae</i>. Biotechnol Biofuels 11:180 PMID: 29983743
- Semkiv MV, et al. (2017) Metabolic engineering for high glycerol production by the anaerobic cultures of Saccharomyces cerevisiae. Appl Microbiol Biotechnol 101(11):4403-4416 PMID: 28280870
- Kim S, et al. (2016) Redirection of pyruvate flux toward desired metabolic pathways through substrate channeling between pyruvate kinase and pyruvate-converting enzymes in Saccharomyces cerevisiae. Sci Rep 6:24145 PMID: 27052099
- Murashchenko L, et al. (2016) Overexpression of the truncated version of ILV2 enhances glycerol production in Saccharomyces cerevisiae. Yeast 33(8) PMID: 26990811
- van Bergen B, et al. (2016) α,β-Dicarbonyl reduction is mediated by the Saccharomyces Old Yellow Enzyme. FEMS Yeast Res 16(5) PMID: 27400981
- Kim S and Hahn JS (2015) Efficient production of 2,3-butanediol in Saccharomyces cerevisiae by eliminating ethanol and glycerol production and redox rebalancing. Metab Eng 31:94-101 PMID: 26226562
- Costa IR, et al. (2014) Metazoan remaining genes for essential amino acid biosynthesis: sequence conservation and evolutionary analyses. Nutrients 7(1):1-16 PMID: 25545100
- Du Y, et al. (2014) Threonine deaminase MoIlv1 is important for conidiogenesis and pathogenesis in the rice blast fungus Magnaporthe oryzae. Fungal Genet Biol 73:53-60 PMID: 25307542
- Lian J, et al. (2014) Metabolic engineering of a Saccharomyces cerevisiae strain capable of simultaneously utilizing glucose and galactose to produce enantiopure (2R,3R)-butanediol. Metab Eng 23:92-9 PMID: 24525332
- Du Y, et al. (2013) Acetolactate synthases MoIlv2 and MoIlv6 are required for infection-related morphogenesis in Magnaporthe oryzae. Mol Plant Pathol 14(9):870-84 PMID: 23782532
- Richie DL, et al. (2013) Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents. Antimicrob Agents Chemother 57(5):2272-80 PMID: 23478965
- Frelin O, et al. (2012) Identification of mitochondrial thiamin diphosphate carriers from Arabidopsis and maize. Funct Integr Genomics 12(2):317-26 PMID: 22426856
- Lee WH, et al. (2012) Isobutanol production in engineered Saccharomyces cerevisiae by overexpression of 2-ketoisovalerate decarboxylase and valine biosynthetic enzymes. Bioprocess Biosyst Eng 35(9):1467-75 PMID: 22543927
- Kingsbury JM and McCusker JH (2010) Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin. Microbiology (Reading) 156(Pt 3):929-939 PMID: 20019084
- Nielsen DR, et al. (2010) Metabolic engineering of acetoin and meso-2, 3-butanediol biosynthesis in E. coli. Biotechnol J 5(3):274-84 PMID: 20213636
- Wang J, et al. (2010) Construction of amylolytic industrial brewing yeast strain with high glutathione content for manufacturing beer with improved anti-staling capability and flavor. J Microbiol Biotechnol 20(11):1539-45 PMID: 21124060
- Liu Z, et al. (2008) Mutagenizing brewing yeast strain for improving fermentation property of beer. J Biosci Bioeng 106(1):33-8 PMID: 18691528
- Wang D, et al. (2008) Genetic modification of industrial yeast strains to obtain controllable NewFlo flocculation property and lower diacetyl production. Biotechnol Lett 30(11):2013-8 PMID: 18581063
- Lee YT and Duggleby RG (2006) Mutations in the regulatory subunit of yeast acetohydroxyacid synthase affect its activation by MgATP. Biochem J 395(2):331-6 PMID: 16390333
- McCourt JA and Duggleby RG (2006) Acetohydroxyacid synthase and its role in the biosynthetic pathway for branched-chain amino acids. Amino Acids 31(2):173-210 PMID: 16699828
- Ambrona J, et al. (2005) Sulfometuron resistance as a genetic marker for yeast populations in wine fermentations. J Agric Food Chem 53(19):7438-43 PMID: 16159170
- Fernández-González M, et al. (2005) Engineering of an oenological Saccharomyces cerevisiae strain with pectinolytic activity and its effect on wine. Int J Food Microbiol 102(2):173-83 PMID: 15992616
- Kingsbury JM, et al. (2004) Cryptococcus neoformans Ilv2p confers resistance to sulfometuron methyl and is required for survival at 37 degrees C and in vivo. Microbiology (Reading) 150(Pt 5):1547-1558 PMID: 15133116
- Liu Z, et al. (2004) Constructing an amylolytic brewing yeast Saccharomyces pastorianus suitable for accelerated brewing. J Biosci Bioeng 98(6):414-9 PMID: 16233729
- Pang SS, et al. (2003) Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase. J Biol Chem 278(9):7639-44 PMID: 12496246
- Marobbio CM, et al. (2002) Identification and reconstitution of the yeast mitochondrial transporter for thiamine pyrophosphate. EMBO J 21(21):5653-61 PMID: 12411483
- Sergienko EA and Jordan F (2001) Catalytic acid-base groups in yeast pyruvate decarboxylase. 2. Insights into the specific roles of D28 and E477 from the rates and stereospecificity of formation of carboligase side products. Biochemistry 40(25):7369-81 PMID: 11412091
- Jia MH, et al. (2000) Global expression profiling of yeast treated with an inhibitor of amino acid biosynthesis, sulfometuron methyl. Physiol Genomics 3(2):83-92 PMID: 11015603
- Chipman D, et al. (1998) Biosynthesis of 2-aceto-2-hydroxy acids: acetolactate synthases and acetohydroxyacid synthases. Biochim Biophys Acta 1385(2):401-19 PMID: 9655946
- Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 PMID: 9655908
- Duggleby RG (1997) Identification of an acetolactate synthase small subunit gene in two eukaryotes. Gene 190(2):245-9 PMID: 9197540
- Cullin C, et al. (1996) Functional analysis of YCL09C: evidence for a role as the regulatory subunit of acetolactate synthase. Yeast 12(15):1511-8 PMID: 8972574
- Bekkaoui F, et al. (1993) Isolation and structure of an acetolactate synthase gene from Schizosaccharomyces pombe and complementation of the ilv2 mutation in Saccharomyces cerevisiae. Curr Genet 24(6):544-7 PMID: 8299177
- Xiao W and Rank GH (1990) Branched chain amino acid regulation of the ILV2 locus in Saccharomyces cerevisiae. Genome 33(4):596-603 PMID: 2227406
- Green JB (1989) Pyruvate decarboxylase is like acetolactate synthase (ILV2) and not like the pyruvate dehydrogenase E1 subunit. FEBS Lett 246(1-2):1-5 PMID: 2651151
- Poulsen C and Stougaard P (1989) Purification and properties of Saccharomyces cerevisiae acetolactate synthase from recombinant Escherichia coli. Eur J Biochem 185(2):433-9 PMID: 2684671
- Maiti SN, et al. (1988) Effect of valine and the herbicide sulfometuron methyl on acetolactate synthase activity in nuclear and plasmid-borne sulphometuron methyl resistant Saccharomyces cerevisiae strains. Can J Microbiol 34(5):680-5 PMID: 3061621
- Xiao W and Rank GH (1988) Generation of an ilv bradytrophic phenocopy in yeast by antisense RNA. Curr Genet 13(4):283-9 PMID: 2455608
- Xiao W and Rank GH (1988) The yeast ILV2 gene is under general amino acid control. Genome 30(6):984-6 PMID: 3069583
- Falco SC and Dumas KS (1985) Genetic analysis of mutants of Saccharomyces cerevisiae resistant to the herbicide sulfometuron methyl. Genetics 109(1):21-35 PMID: 3881312
- Falco SC, et al. (1985) Nucleotide sequence of the yeast ILV2 gene which encodes acetolactate synthase. Nucleic Acids Res 13(11):4011-27 PMID: 2989783