Gene Ontology Help

MEI5-SAE3 recombination assembly factor complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Regulates homologous recombination repair by binding to, and stimulating, the homologous DNA 3-stranded exchange activity of meiosis-specific DMC1 (P25453). Enhances DMC1 loading onto RPA-coated single-stranded DNA, at a RAD51 foci and that it enhances DMC1-mediated D-loop formation. The coordinated actions of RAD51 and DMC1 are considered to play a critical role in homology searches and strand exchange during recombination.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

DNA metabolic process, DNA recombination, cellular component assembly, cellular nitrogen compound metabolic process, protein-containing complex assembly, chromosome, nuclear chromosome, organelle