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| Dataset | Description | Keywords | Number of Conditions | Reference |
|---|---|---|---|---|
| A combined genetic and genomic approach uncovers molecular basis of wine yeast fermentation traits | Industrial wine yeast strains possess specific abilities to ferment under stressing conditions and give a suitable aromatic outcome | fermentation, nitrogen utilization | 40 | Ambroset C, et al. (2011) PMID:22384338 |
| A genetic approach of wine yeast fermentation capacity in nitrogen-starvation reveals the key role of nitrogen signaling. | In conditions of nitrogen limitation, Saccharomyces cerevisiae strains differ in their fermentation capacities, due to differences in their nitrogen requirements | nitrogen utilization, fermentation | 8 | Brice C, et al. (2014) PMID:24947828 |
| A tRNA modification balances carbon and nitrogen metabolism by regulating phosphate homeostasis, to couple metabolism to cell cycle progression. | Cells must appropriately sense and integrate multiple metabolic resources to commit to proliferation. Here, we report that cells regulate nitrogen (amino acid) and carbon metabolic homeostasis through tRNA U34-thiolation. Despite amino acid sufficiency, tRNA-thiolation deficient cells appear amino acid starved. In these cells, carbon flux towards nucleotide synthesis decreases, and trehalose synthesis increases, resulting in metabolic a starvation-signature. Thiolation mutants have only minor translation defects. However, these cells exhibit strongly decreased expression of phosphate homeostasis genes, mimicking a phosphate-limited state. Reduced phosphate enforces a metabolic switch, where glucose-6-phosphate is routed towards storage carbohydrates. Notably, trehalose synthesis, which releases phosphate and thereby restores phosphate availability, is central to this metabolic rewiring. Thus, cells use thiolated tRNAs to perceive amino acid sufficiency, and balance amino acid and carbon metabolic flux to maintain metabolic homeostasis, by controlling phosphate availability. These results further biochemical explain how phosphate availability determines a switch to a ‘starvation-state’. | carbon utilization, nitrogen utilization, phosphorus utilization, RNA structure, sulfur utilization | 2 | Gupta R, et al. (2019) PMID:31259691 |
| Carbon-limited anaerobic/aerobic growth of S.cerevisiae-New set | Addition of 3 new arrays made from carbon limited chemostat of CENPK113-7D and 3 new arrays made from aerobic carbon limited chemostat of CENPK113-7D Complmentary data to the data of the serie GSE1723. | carbon utilization, fermentation, nitrogen utilization, oxygen level alteration, phosphorus utilization, respiration, sulfur utilization | 30 | Knijnenburg TA, et al. (2007) PMID:17241460 |
| Deletion of the Saccharomyces cerevisiae ARO8 gene, encoding an aromatic amino acid transaminase, enhances phenylethanol production from glucose | Its characteristic rose-like aroma makes phenylethanol a popular ingredient in foods, beverages and cosmetics | nutrient utilization, nitrogen utilization | 4 | Romagnoli G, et al. (2015) PMID:24733517 |
| Dynamic mRNA gene expression during a nutritional downshift from glutamine to proline | Dynamic mRNA gene expression from the wildtype YSBN6 during a nutritional downshift from glutamine to proline | nitrogen utilization | 15 | Oliveira AP, et al. (2015) PMID:25888284 |
| Dynamic mRNA gene expression during a nutritional upshift from proline to glutamine | Dynamic mRNA gene expression from the wildtype YSBN6 during a nutritional upshift from proline to glutamine | nitrogen utilization | 14 | Oliveira AP, et al. (2015) PMID:25888284 |
| Dynamics of Nitrogen-regulated Gene Expression Reveals a Reciprocal Relationship between Cell Growth Rate and Nitrogen Catabolism | Cell growth rate is regulated in response to resource availability including the abundance, and molecular form, of essential nutrients | nitrogen utilization | 102 | Airoldi EM, et al. (2016) PMID:26941329 |
| Effect of nitrogen addition timing of an enological yeast strain gene expression | The aim of this study was to evaluate the effect of timing of nitrogen added on a Saccharomyces cerevisiae yeast wine strain. We studied several addition timings and evaluated gene expression at different times after nitrogen addition (30min and 2h). We found that there were no major differences between the two samples after addition. 305 induced genes were common to both addition timings and represented amino acid biosynthetic functions. 147 induced genes were only induced after an addition made at the beginning of the stationary phase and 142 exclusively after an addition made at the end of the stationary phase. These genes represented translation and ribosomal RNA synthesis functions respectively. 150 genes were only repressed after an addition made at the beginning of the stationary phase and represented functions of responses to stress and nutritional deficiencies but also oxidoreductase activity. The repressed genes common to both timings (284) represented the same functions. Finally, the 127 genes only repressed after an addition made close to the end of the fermentation represented functions coding for lipid metabolism and cell wall organization. | nitrogen utilization | 24 | Godillot J, et al. (2022) PMID:35273585 |
| Effect of twenty-one different nitrogen sources on global gene expression in the yeast Saccharomyces cerevisiae | We have applied whole-genome microarray hybridization to compare the transcriptome of wild-type yeast strain _1278b during growth on a minimal medium containing 21 different single nitrogen sources including urea used as a reference condition. | nitrogen utilization | 40 | Godard P, et al. (2007) PMID:17308034 |