FUS3 / YBL016W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; isolated based on a bilateral cell fusion defect; null mutant has reduced mating efficiency and is unable to undergo pheromone induced G1 arrest; overexpression increases pheromone sensitivity; null mutant displays decreased autophagy and endocytosis; null mutant is hyperfilamentous and disrupts the nuclear localization of Sks1p and Ksp1p after induction of filamentous growth

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources