ERD2 / YBL040C Homology


Standard Name
ERD2 1 2
Systematic Name
YBL040C
SGD ID
SGD:S000000136
Feature Type
ORF , Verified
Description
HDEL receptor; an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins 1 2 3 4
Name Description
Endoplasmic reticulum Retention Defective 5
Comparative Info

Homologs

Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.


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Species Gene ID Gene name Source

Functional Complementation

Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).

3 entries for 3 complements


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SpeciesGene IDStrain backgroundDirectionDetailsSourceReference
Homo sapiensHGNC:6304S288Cother complements yeastHuman KDELR1 complements the inviability of the S. cerevisiae erd2 haploid knockout post-sporulation using a heterozygous diploid knockout deletion (hetKO); verified by isolating a haploid humanized yeast gene knockout strain in a reassay and verifying plasmid dependence; KDELR1 is one member of a 1:>2 orthogroup. SGDLaurent JM, et al. (2020)
PMID:32421706
Homo sapiensHGNC:6305S288Cother complements yeastHuman KDELR2 complements the inviability of the S. cerevisiae erd2 haploid knockout post-sporulation using a heterozygous diploid knockout deletion (hetKO); verified by isolating a haploid humanized yeast gene knockout strain in a reassay and verifying plasmid dependence; KDELR2 is one member of a 1:>2 orthogroup.SGDLaurent JM, et al. (2020)
PMID:32421706
Homo sapiensHGNC:6306S288Cother complements yeastHuman KDELR3 complements the inviability of the S. cerevisiae erd2 haploid knockout post-sporulation using a heterozygous diploid knockout deletion (hetKO); verified by isolating a haploid humanized yeast gene knockout strain in a reassay and verifying plasmid dependence; KDELR3 is one member of a 1:>2 orthogroup. SGDLaurent JM, et al. (2020)
PMID:32421706
Showing 1 to 3 of 3 entries

Fungal Homologs

Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.


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Species Gene ID Gene name Description Source

External Identifiers

List of external identifiers for the protein from various database sources.

23 entries for 10 sources


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External IDSource
AN11226AspGD
orf19.2756CGD
7718DIP
6319431GenBank/EMBL/DDBJ
CAA55054.1GenBank/EMBL/DDBJ
CAA84860.1GenBank/EMBL/DDBJ
AAA68907.1GenBank/EMBL/DDBJ
Z35801GenBank/EMBL/DDBJ
X78214GenBank/EMBL/DDBJ
119545GenBank/EMBL/DDBJ
Showing 1 to 10 of 23 entries

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