Literature Help
AAR2 / YBL074C Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Yan C, et al. (2016) Structure of a yeast activated spliceosome at 3.5 Å resolution. Science 353(6302):904-11 PMID:27445306
- Santos K, et al. (2015) Crystallization and biochemical characterization of the human spliceosomal Aar2-Prp8(RNaseH) complex. Acta Crystallogr F Struct Biol Commun 71(Pt 11):1421-8 PMID:26527271
- Galej WP, et al. (2013) Crystal structure of Prp8 reveals active site cavity of the spliceosome. Nature 493(7434):638-43 PMID:23354046
- Nguyen TH, et al. (2013) Structural basis of Brr2-Prp8 interactions and implications for U5 snRNP biogenesis and the spliceosome active site. Structure 21(6):910-19 PMID:23727230
- Weber G, et al. (2013) Structural basis for dual roles of Aar2p in U5 snRNP assembly. Genes Dev 27(5):525-40 PMID:23442228
- Weber G, et al. (2011) Mechanism for Aar2p function as a U5 snRNP assembly factor. Genes Dev 25(15):1601-12 PMID:21764848
- Ben-Aroya S, et al. (2010) Proteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair. PLoS Genet 6(2):e1000852 PMID:20174551
- Gottschalk A, et al. (2001) The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p. RNA 7(11):1554-65 PMID:11720285
- Nakazawa N, et al. (1991) AAR2, a gene for splicing pre-mRNA of the MATa1 cistron in cell type control of Saccharomyces cerevisiae. Mol Cell Biol 11(11):5693-700 PMID:1922071
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Barthel T, et al. (2022) Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites. J Med Chem 65(21):14630-14641 PMID:36260741
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Shcherbakova I, et al. (2013) Alternative spliceosome assembly pathways revealed by single-molecule fluorescence microscopy. Cell Rep 5(1):151-65 PMID:24075986
- Schwer B, et al. (2011) Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells. Nucleic Acids Res 39(15):6715-28 PMID:21558325
- Alexander RD, et al. (2010) Splicing-dependent RNA polymerase pausing in yeast. Mol Cell 40(4):582-93 PMID:21095588
- Ungar L, et al. (2009) A genome-wide screen for essential yeast genes that affect telomere length maintenance. Nucleic Acids Res 37(12):3840-9 PMID:19386622
- Bellare P, et al. (2008) A role for ubiquitin in the spliceosome assembly pathway. Nat Struct Mol Biol 15(5):444-51 PMID:18425143
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Boon KL, et al. (2007) prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast. Nat Struct Mol Biol 14(11):1077-83 PMID:17934474
- Boon KL, et al. (2006) Prp8p dissection reveals domain structure and protein interaction sites. RNA 12(2):198-205 PMID:16373487
- Pandit S, et al. (2006) Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc Natl Acad Sci U S A 103(37):13700-5 PMID:16945917
- Logghe M, et al. (1994) The two genes encoding yeast ribosomal protein S8 reside on different chromosomes, and are closely linked to the hsp70 stress protein genes SSA3 and SSA4. Yeast 10(8):1093-1100 PMID:7992509
Reviews
No reviews curated.
Download References (.nbib)
- Yan C, et al. (2019) Molecular Mechanisms of pre-mRNA Splicing through Structural Biology of the Spliceosome. Cold Spring Harb Perspect Biol 11(1) PMID:30602541
- Nguyen TH, et al. (2016) CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast. Curr Opin Struct Biol 36:48-57 PMID:26803803
- Chen HC and Cheng SC (2012) Functional roles of protein splicing factors. Biosci Rep 32(4):345-59 PMID:22762203
- Bergkessel M, et al. (2009) SnapShot: Formation of mRNPs. Cell 136(4):794, 794.e1 PMID:19239896
- Wahl MC, et al. (2009) The spliceosome: design principles of a dynamic RNP machine. Cell 136(4):701-18 PMID:19239890
- Neubauer G (2005) The analysis of multiprotein complexes: the yeast and the human spliceosome as case studies. Methods Enzymol 405:236-63 PMID:16413317
- Harashima S and Kaneko Y (2001) Application of the PHO5-gene-fusion technology to molecular genetics and biotechnology in yeast. J Biosci Bioeng 91(4):325-38 PMID:16233000
- Burge CB et al. (1999) "Splicing of precursors to mRNAs by the spliceosomes." Pp. 525-560 in The RNA World, Second Edition, edited by Gesteland RF, Cech TR, Atkins JF. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
- Woolford JL and Peebles CL (1992) RNA splicing in lower eukaryotes. Curr Opin Genet Dev 2(5):712-9 PMID:1333856
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Mishra PK, et al. (2023) Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability. Mol Biol Cell 34(10):ar99 PMID:37436802
- Mount HO, et al. (2018) Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. PLoS Genet 14(4):e1007319 PMID:29702647
- Babour A, et al. (2016) The Chromatin Remodeler ISW1 Is a Quality Control Factor that Surveys Nuclear mRNP Biogenesis. Cell 167(5):1201-1214.e15 PMID:27863241
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Kırlı K, et al. (2015) A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife 4 PMID:26673895
- Galej WP, et al. (2013) Crystal structure of Prp8 reveals active site cavity of the spliceosome. Nature 493(7434):638-43 PMID:23354046
- Nguyen TH, et al. (2013) Structural basis of Brr2-Prp8 interactions and implications for U5 snRNP biogenesis and the spliceosome active site. Structure 21(6):910-19 PMID:23727230
- van Pel DM, et al. (2013) Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. G3 (Bethesda) 3(2):273-82 PMID:23390603
- Weber G, et al. (2013) Structural basis for dual roles of Aar2p in U5 snRNP assembly. Genes Dev 27(5):525-40 PMID:23442228
- Schwer B, et al. (2011) Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells. Nucleic Acids Res 39(15):6715-28 PMID:21558325
- Weber G, et al. (2011) Mechanism for Aar2p function as a U5 snRNP assembly factor. Genes Dev 25(15):1601-12 PMID:21764848
- Boon KL, et al. (2007) prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast. Nat Struct Mol Biol 14(11):1077-83 PMID:17934474
- Boon KL, et al. (2006) Prp8p dissection reveals domain structure and protein interaction sites. RNA 12(2):198-205 PMID:16373487
- Gavin AC, et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature 440(7084):631-6 PMID:16429126
- Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43 PMID:16554755
- Pandit S, et al. (2006) Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc Natl Acad Sci U S A 103(37):13700-5 PMID:16945917
- Ptacek J, et al. (2005) Global analysis of protein phosphorylation in yeast. Nature 438(7068):679-84 PMID:16319894
- Krogan NJ, et al. (2004) High-definition macromolecular composition of yeast RNA-processing complexes. Mol Cell 13(2):225-39 PMID:14759368
- Gavin AC, et al. (2002) Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415(6868):141-7 PMID:11805826
- Gottschalk A, et al. (2001) The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p. RNA 7(11):1554-65 PMID:11720285
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Forster DT, et al. (2022) BIONIC: biological network integration using convolutions. Nat Methods 19(10):1250-1261 PMID:36192463
- Ohnuki S and Ohya Y (2018) High-dimensional single-cell phenotyping reveals extensive haploinsufficiency. PLoS Biol 16(5):e2005130 PMID:29768403
- Hendry JA, et al. (2015) Leveraging DNA damage response signaling to identify yeast genes controlling genome stability. G3 (Bethesda) 5(5):997-1006 PMID:25721128
- Ostrow AZ, et al. (2014) Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics. PLoS One 9(2):e87647 PMID:24504085
- Pimentel C, et al. (2012) The role of the Yap5 transcription factor in remodeling gene expression in response to Fe bioavailability. PLoS One 7(5):e37434 PMID:22616008
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Ungar L, et al. (2009) A genome-wide screen for essential yeast genes that affect telomere length maintenance. Nucleic Acids Res 37(12):3840-9 PMID:19386622
- Ben-Aroya S, et al. (2008) Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae. Mol Cell 30(2):248-58 PMID:18439903
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- MacIsaac KD, et al. (2006) An improved map of conserved regulatory sites for Saccharomyces cerevisiae. BMC Bioinformatics 7:113 PMID:16522208
- Lum PY, et al. (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37 PMID:14718172
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549