TRM7 / YBR061C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant is sensitive to H2O2; trm7-A26P disease-analogous mutation causes reduced 2'-O-methylation of the anticodon loop of tRNA-Phe; in large-scale studies, the null mutant displays shorter chronological lifespan, decreased competitive fitness, poor growth on galactose, increased transposition of transposable elements, and altered resistance to a variety of chemicals

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

38 entries for 19 phenotypes

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources